Evidence map›Paper›PMID 40903631›Full record

ReviewStem cell reviews and reports2025

Strategies in Tissue Regenerative Engineering for the Treatment of Human Infertility.

Ria Margiana, Harikumar Pallathadka, Sofiene Mansouri, Qutaiba A Qasim, Ashwani Kumar, Abhinav Kumar, Atreyi Pramanik, Ahmed Hussein Zwamel, Hamza Fadhel Hamzah, Israa Hussein Mohammed

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews and reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ria MargianaDepartment of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Harikumar PallathadkaManipur International University, Imphal, Manipur, India. harikumar@miu.edu.in.ORCID 0000-0002-0705-9035
Sofiene MansouriDepartment of Biomedical Technology, College of Applied Medical Sciences in Al- Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia. fertility48@gmail.com.ORCID 0000-0002-6191-3095
Qutaiba A QasimCollege of pharmacy, Al-Ayen University, Thi-Qar, Iraq.
Ashwani KumarDepartment of Life Sciences, School of Sciences, Jain (Deemed-to-be) University, Bengaluru, 560069, Karnataka, India.
Abhinav KumarDepartment of Nuclear and Renewable Energy, Ural Federal University Named after the First President of Russia Boris Yeltsin, Ekaterinburg, 620002, Russia.
Atreyi PramanikSchool of Applied and Life Sciences, Divison of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India.
Ahmed Hussein ZwamelMedical laboratory technique college, the Islamic University, Najaf, Iraq.
Hamza Fadhel HamzahDepartment of Medical Laboratories Technology, Hamza Fadhel Hamzah, Nisour University College, Baghdad, Iraq.
Israa Hussein Mohammedcollege of nursing, National University of Science and Technology, Dhi Qar, Iraq.

Funding

Prince Sattam bin Abdulaziz University PSAU/2024/R/1445
6 · The paper itself

Abstract

Regenerative engineering (RE) is the convergence of advanced stem cell science, material science, physics, clinical translation, and developmental biology to regenerate organ and complex tissue systems. It is a development of tissue engineering, which was first advanced as a method of restoration and repair of human tissue. In recent years, advances in regenerative techniques have shown promise in treating various clinical problems using existing advanced technology to harness the body's therapeutic and regenerative abilities. Currently, the treatment of human infertility focuses on regenerative tissue engineering methods. This article reviews recent developments in tissue engineering, focusing on different sources of stem cells, oxygen tension, inductive factors such as growth factors, biomaterial learning and mechanical stimuli, and internal and external regulatory mechanisms that control proliferation and differentiation. The extracellular matrix plays a crucial role in tissue engineering by providing a supportive environment for the formation of blood and lymphatic vessels, serving as an ideal substrate for cell transplantation and growth. The application of scaffolds in tissue engineering has demonstrated significant therapeutic promise for addressing human infertility. In contemporary society, numerous couples face challenges related to infertility, which can stem from various factors, including uterine injuries, the effects of chemotherapy, and intrauterine adhesions. This report presents an innovative scaffold-based approach to tissue engineering aimed at treating infertility.

Indexed as

InfertilityRegenerative MedicineTissue EngineeringAnimalsCell DifferentiationExtracellular MatrixFemaleHumansRegenerationStem CellsTissue ScaffoldsBiomaterialsHuman infertilityRegenerative engineering (RE)Stem cellTissue engineering (TE)

Identifiers

PMID40903631

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.