ArticleFood science & nutrition2025
Omega-3 Fatty Acids Supplementation and Neuroprotection, Inflammation, Fatigue, and Physical Activity in Multiple Sclerosis: A Randomized Controlled Trial.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Immunonutritional biomarkers in osteoarthritis: mechanistic insights and prognostic potential.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Omega-3 fatty acids have neuroprotective properties. The present study aimed to evaluate the influence of omega-3 fatty acids supplementation on the serum levels of brain-derived neurotrophic factor (BDNF), high-sensitivity C-reactive protein (hs-CRP), physical activity, and chronic fatigue in patients with multiple sclerosis (MS). In a double-blind, placebo-controlled trial, 68 MS patients were randomly assigned to the intervention group receiving omega-3 fatty acids soft gels (1000 mg) twice a day for 12 weeks and the placebo group similarly taking paraffin soft gels. Serum concentrations of BDNF and hs-CRP were assessed before and after the intervention. Chronic fatigue, physical activity, and dietary intake of omega-3 fatty acids were evaluated. Initial comparisons between the intervention and control groups showed no significant differences for BDNF and hs-CRP levels (
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