Evidence map›Paper›PMID 40905366›Full record

ArticleEuropean heart journal. Quality of care & clinical outcomes2025

The assessment and management of patients with type 2 myocardial infarction: an international Delphi study.

Caelan Taggart, Amy V Ferry, Andrew R Chapman, Stacey D Schulberg, Anda Bularga, Ryan Wereski, Jasper Boeddinghaus, Dorien M Kimenai, Matthew T H Lowry, Derek P Chew and 28 more

Abstract read
In one paragraph

Article in European heart journal. Quality of care & clinical outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

38 authors.

Caelan TaggartBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.ORCID 0000-0001-7379-5439
Amy V FerryBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.
Andrew R ChapmanBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.
Stacey D SchulbergBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.
Anda BulargaBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.ORCID 0000-0002-5530-527X
Ryan WereskiBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.
Jasper BoeddinghausBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.
Dorien M KimenaiBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.ORCID 0000-0003-1591-1352
Matthew T H LowryBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.
Derek P ChewVictorian Heart Hospital/Victorian Heart Institute, Monash University, Melbourne, VIC 3168, Australia.
Louise CullenFaculty of Medicine, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-6611-8229
Lori B DanielsDepartment of Medicine, University of California, San Diego, CA 92093, USA.
P J DevereauxDepartments of Health Research Methods, Evidence, and Impact and Medicine, McMaster University, Hamilton, Canada L8S 4L8.
John FrenchDepartment of Cardiology, University of New South Wales and Liverpool Hospital, NSW 2170, Australia.
Hanna K GagginDivision of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Thao HuynhMcGill University Health Centre, Montreal, Quebec, Canada H3G 1A4.
Laurent JacquinEmergency Medicine Department, Hospices Civils de Lyon, Edouard Herriot Hospital, Lyon 69003, France.
Allan S JaffeDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA.
Tomas JernbergDepartment of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm 182 88, Sweden.ORCID 0000-0003-1695-379X
Ran KoronowskiDepartment of Cardiology, Rabin Medical Center, Petah Tikva, Faculty of Medicine, Tel Aviv University, Tel Aviv 49100, Israel.
Cian McCarthyDivision of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
James McCordHeart and Vascular Institute, Henry Ford Hospital, Detroit, MI 48307, USA.
Mamas A MamasKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele ST5 5BG, United Kingdom.ORCID 0000-0001-9241-8890
Hans MickleyDepartment of Cardiology, Odense University Hospital, Odense 5000, Denmark.
David A MorrowCardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Christian MuellerDepartment of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, Basel 4031, Switzerland.ORCID 0000-0002-3531-5243
L Kristin NewbyDepartment of Medicine, Division of Cardiology, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA.
William ParsonageAustralian Centre for Health Services Innovation, Queensland University of Technology, Brisbane, QLD 4059, Australia.
Claire E RaphaelDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-2206-0413
Aiman SmerCHI-Health-Creighton University School of Medicine, Omaha, NE 68131, USA.
Stephen W SmithDepartment of Emergency Medicine, Hennepin County Medical Center and University of Minnesota, Minneapolis, MN 55415, USA.
Yader SandovalMinneapolis Heart Institute, Abbott Northwestern Hospital, Centre for Coronary Artery Disease, Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA.
Nathaniel R SmilowitzLeon H. Charney Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA.
Harvey WhiteTe Toka Tumai, Green Lane Cardiovascular Services, Auckland City Hospital, Te Whatu Ora-Health, Auckland 1142, New Zealand.ORCID 0000-0001-7712-6750
Kai M EggersDepartment of Medical Sciences, Uppsala University, Uppsala 75123, Sweden.
Bertil LindahlDepartment of Medical Sciences, Uppsala University, Uppsala 75123, Sweden.ORCID 0000-0002-5795-0061
Kristian ThygesenDepartment of Cardiology, Aarhus University Hospital, Aarhus 8200, Denmark.ORCID 0000-0002-3674-1308
Nicholas L MillsBHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom.ORCID 0000-0003-0533-7991

Funding

British Heart Foundation CH/F/21/90010British Heart Foundation Clinical Research Training Fellowship FS/CRTF/21/2473British Heart Foundation Intermediate Basic Science Research Fellowship FS/IBSRF/23/25161Programme Grant RG/20/10/34966Research Excellence Award MR/V007017/1Research Excellence Award RE/18/5/34216the British Heart Foundation CH/F/21/90010UK Research and Innovation Medical Research Council
6 · The paper itself

Abstract

aimsType 2 myocardial infarction due to myocardial oxygen supply-demand imbalance is associated with poor outcomes. There are no guidelines to inform care for these patients. The consensus on the assessment and management of type 2 myocardial infarction is gained. METHODS AND

resultsAn international e-Delphi study including experts in type 2 myocardial infarction identified through systematic review was conducted. Participants were asked to describe their approach to (i) definition and diagnosis, (ii) risk stratification, (iii) assessment of coronary artery disease and cardiac function, (iv) specialty management, (v) treatment and secondary prevention, and (vi) communication and rehabilitation. Statements generated in round one were circulated, with consensus defined a priori as ≥70% agreement on a 5-point Likert scale. Where no consensus was reached, statements were amended and recirculated for a final round. The response rate was 56% (38/68), 54% (37/68), and 72% (49/68) in the first, second, and third rounds, respectively. Following the first round, 67 unique statements were generated across six domains. Overall, consensus was achieved on 64% (43/67) of statements. Consensus was achieved for 42% (5/12) of statements on the diagnosis of type 2 myocardial infarction, 75% (3/4) on risk stratification, 50% (9/18) on the assessment of coronary artery disease and cardiac function, 60% (6/10), on specialty management, 100% (9/9) on treatment and secondary prevention, and 79% (11/15) on communication and rehabilitation.

conclusionConsensus was obtained across a number of domains for the assessment and management of patients with type 2 myocardial infarction. However, there was limited agreement amongst experts on the diagnostic criteria, which may benefit from refinement.

Indexed as

Disease ManagementMyocardial InfarctionConsensusDelphi TechniqueHumansRisk AssessmentSecondary PreventionConsensusDelphi studyManagementMyocardial infarctionType 2 myocardial infarction

Identifiers

PMID40905366
PMCPMC12714377

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.