Evidence map›Paper›PMID 40906180›Full record

ArticleBiology2025

Bisphenol E Neurotoxicity in Zebrafish Larvae: Effects and Underlying Mechanisms.

Kaicheng Gu, Lindong Yang, Yi Jiang, Zhiqiang Wang, Jiannan Chen

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaicheng GuSchool of life Science, Nanjing Normal University, No. 1 Wenyuan Road, Qixia District, Nanjing 210023, China.ORCID 0009-0004-3265-2748
Lindong YangDepartment of Obstetrics and Gynecology, School of Medicine, Nanjing University, 305 Zhongshan East Road, Xuanwu District, Nanjing 210018, China.
Yi JiangDepartment of Animal Science, College of Animal Science, Hebei North University, Zhangjiakou 075000, China.
Zhiqiang WangDepartment of Anorectal Surgery, Tianjin Medical University, No. 23 Pingjiang Road, Hexi District, Tianjin 300211, China.
Jiannan ChenJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences Nanjing Normal University, 1 WenYuan Road, Nanjing 210023, China.

Funding

Tianjin Natural Science Foundation 21JCYBJC01730
6 · The paper itself

Abstract

As typical environmental hormones, endocrine-disrupting chemicals (EDCs) have become a global environmental health issue of high concern due to their property of interfering with the endocrine systems of organisms. As a commonly used substitute for bisphenol A (BPA), bisphenol E (BPE) has been frequently detected in environmental matrices such as soil and water in recent years. Existing research has unveiled the developmental and reproductive toxicity of BPE; however, only one in vitro cellular experiment has preliminarily indicated potential neurotoxic risks, with its underlying mechanisms remaining largely unelucidated in the current literature. Potential toxic mechanisms and action targets of BPE were predicted using the zebrafish model via network toxicology and molecular docking, with RT-qPCRs being simultaneously applied to uncover neurotoxic effects and associated mechanisms of BPE. A significant decrease (

Indexed as

bisphenol Eendocrine-disrupting chemicalsnetwork toxicologyneurotoxicity

Identifiers

PMID40906180
PMCPMC12383493

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.