Evidence map›Paper›PMID 40906231›Full record

ArticleBiology2025

Hydrogen-Rich Water Attenuates Diarrhea in Weaned Piglets via Oxidative Stress Alleviation.

Pengfei Zhang, Jingyu Yang, Zhuoda Lu, Qianxi Liang, Xing Yang, Junchao Wang, Jinbiao Guo, Yunxiang Zhao

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Microorganisms · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pengfei ZhangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Jingyu YangSchool of Life Sciences and Engineering, Foshan University, Foshan 528231, China.
Zhuoda LuCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Qianxi LiangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Xing YangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Junchao WangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Jinbiao GuoSchool of Life Sciences and Engineering, Foshan University, Foshan 528231, China.
Yunxiang ZhaoCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0009-0005-9620-7640

Funding

Guangxi Innovation Team Initiative under China's National Agricultural Technology System nycytxgxcxtd-2023-15-03Guangxi Key Technologies R&D Program Guinongke AB241484033National Key Research and Development Program of China 2022YFD1601307
6 · The paper itself

Abstract

Early weaning of piglets elicits weaning stress, which in turn induces oxidative stress and consequently impairs growth and development. Hydrogen-rich water (HRW), characterized by selective antioxidant properties, mitigates oxidative stress damage and serves as an ideal intervention. This study aimed to evaluate the effects of HRW on weaned piglets, specifically investigating its impact on growth performance, diarrhea incidence, antioxidant function, intestinal morphology, gut microbiota, and hepatic metabolites. The results demonstrate that HRW significantly increased the average daily feed intake and significantly reduced the diarrhea rate in weaned piglets. Analysis of serum oxidative stress indicators revealed that HRW significantly elevated the activities of total antioxidant capacity and total superoxide dismutase while significantly decreasing malondialdehyde concentration. Assessment of intestinal morphology showed that HRW significantly increased the villus height to crypt depth ratio in the duodenum, jejunum, and ileum. Microbial analysis indicated that HRW significantly increased the abundance of

Indexed as

diarrheagrowth performancegut microbiotahepatic metabolismhydrogen-rich wateroxidative stressweaned piglets

Identifiers

PMID40906231
PMCPMC12383420

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.