Evidence map›Paper›PMID 40906507›Full record

ArticleMicrobiology spectrum2025

Mutant

Macey Coppinger, Richard F Helm, Liu Yang, Edward G Ruby, David L Popham, Eric V Stabb

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Macey CoppingerDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-0743-873X
Richard F HelmDepartment of Biochemistry, Virginia Tech, Blacksburg, Virginia, USA.
Liu YangDivision of Biosphere Sciences and Engineering, California Institute of Technology, Pasadena, California, USA.
Edward G RubyDivision of Biosphere Sciences and Engineering, California Institute of Technology, Pasadena, California, USA.
David L PophamDepartment of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0002-2614-143X
Eric V StabbDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID 0000-0001-7000-4275

Funding

Vibrio fischeri as a Model for Bacterial ColonizationR37AI050661 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI MARGARET J MC FALL-NGAI, Edward G Ruby · 2018 to 2026
$5.4M
Vibrio colonization determinants in symbiosisR01GM135254 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI MC FALL-NGAI, MARGARET J, RUBY, EDWARD G · 2020 to 2023
$1.9M
National Science Foundation IOS-1557964NIAID NIH HHS R37 AI050661NIGMS NIH HHS R01 GM135254NIH HHS R01-GM135354
6 · The paper itself

Abstract

D-glu is a key component of peptidoglycan (PG) and is essential for growth in most bacteria. To assess constraints on PG evolution and bacterial requirements for D-glu, we sought to artificially evolve PG biosynthesis, leading to either replacement of D-glu in the PG peptide or alternative pathways to D-glu incorporation. We previously found that suppression of D-glu auxotrophy in a

Indexed as

Aliivibrio fischeriBacterial ProteinsGlutamic AcidAllelesCulture MediaMutationPeptidoglycanBacterial ProteinsCulture MediaGlutamic AcidPeptidoglycanAliivibrioD-amino acidsglutamatepeptidoglycanphotobacteriumtransport

Identifiers

PMID40906507
PMCPMC12502697

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.