SynthesisPediatric dermatology
Prevalence, Age of Onset, Age at Diagnosis, and Family History of Hidradenitis Suppurativa in Pediatric Populations: A Systematic Review and Meta-Analysis.
Synthesis in Pediatric dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence, Age of Onset, Age at Diagnosis, and Family History of Hidradenitis Suppurativa in Pediatric Populations: A Systematic Review and Meta-Analysis.Pediatric dermatologyPooled it
- Laboratory Parameters Can Serve as Objective Auxiliary Tools for Assessing Disease Severity in Hidradenitis Suppurativa: A 5-Year Period Single-Center Retrospective Study.Clinical, cosmetic and investigational dermatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by recurrent nodules and abscesses in intertriginous areas, ultimately resulting in scarring and formation of sinus tracts. HS significantly impacts quality of life and can also affect pediatric populations. We aimed to determine the prevalence, family history, age of onset, and age at diagnosis of HS in pediatric populations.
methodsA random-effects meta-analysis of observational studies was conducted following MOOSE guidelines. Five databases were searched through May 2024.
resultsThirty seven observational studies were included, representing 6941 patients from 13 countries. The weighted mean age was 14.7 years (range: 4-18). Ethnoracial distribution included White (36.5%), Black (38.3%), Hispanic (13.9%), Asian (0.8%), Indigenous (0.2%), Middle Eastern (0.7%), multiracial (1.2%), and unspecified populations (8.4%). Among studies reporting severity, 42.5% had Hurley Stage I, 46.3% Stage II, and 11.2% Stage III. The prevalence of HS in pediatric populations was 0.03% (95% CI [0.0001, 0.0005]), with 38% of patients having a family history of HS (95% CI [0.30, 0.45]). Pediatric-onset HS predominantly affects females (78%, 95% CI [0.76, 0.80]). The average age of onset of HS in pediatric populations was 11.3 years (95% CI [10.15, 12.39]), but diagnosis typically occurred at 14.0 years (95% CI [12.65, 15.28]), indicating a delay in diagnosis. Female predominance of HS was associated with earlier age of onset and age at diagnosis, while no significant correlations between family history, age of onset, or age at diagnosis were identified.
conclusionThis study highlights the characteristics of pediatric-onset HS and emphasizes the need for earlier detection to expedite diagnosis and initiation of treatment.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.