Evidence map›Paper›PMID 40908124›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Evaluation of a Sensitive Visual Read Algorithm for Assessing 3R/4R Tau PET Images.

Ruben Smith, Valentina Garibotto, Douglas Hägerström, Jonas Jögi, Tomas Ohlsson, Olof Strandberg, Matteo Tonietto, Shorena Janelidze, Sebastian Palmqvist, Erik Stomrud and 2 more

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ruben SmithClinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden; ruben.smith@med.lu.se.
Valentina GaribottoDivision of Nuclear Medicine and Molecular Imaging, Diagnostic Department, University Hospitals of Geneva, Geneva, Switzerland.
Douglas HägerströmDepartment of Clinical Neurophysiology, Skåne University Hospital, Lund, Sweden.
Jonas JögiDepartment of Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Lund, Sweden.
Tomas OhlssonDepartment of Radiation Physics, Skåne University Hospital, Lund, Sweden; and.
Olof StrandbergClinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.
Matteo ToniettoF. Hoffmann-La Roche Ltd., Basel, Switzerland.
Shorena JanelidzeClinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.
Sebastian PalmqvistClinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.
Erik StomrudClinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.
Gregory KleinF. Hoffmann-La Roche Ltd., Basel, Switzerland.
Oskar HanssonClinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing and validating sensitive visual read algorithms for assessing Alzheimer disease-related tau in tau PET imaging is imperative, considering the implementation of the methodology in clinical practice and trials. Our aim was to compare 2 visual read algorithms for tau PET images to semiquantitative measurements and plasma phospho-tau 217 (p-tau217) status.

Indexed as

AlgorithmsImage Processing, Computer-AssistedPositron-Emission Tomographytau ProteinsAgedAlzheimer DiseaseCarbolinesFemaleHumansMaleMiddle Aged7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleCarbolinestau ProteinsADbiomarkersdiagnostic accuracytau PETvisual read

Identifiers

PMID40908124
PMCPMC12582183

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.