Genetic suppression of precocious transcription termination identifies mutations in essential subunits of the fission yeast cleavage and polyadenylation machinery.
Aleksei Innokentev, Ana M Sanchez, Lauren Bednor, Jill Babor, Beate Schwer, Stewart Shuman
Article in RNA (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
6 authors.
Aleksei InnokentevMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
Ana M SanchezMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.ORCID 0000-0002-9119-7624
Lauren BednorWeill Cornell Graduate School of Medical Sciences, New York, New York 10065, USA.
Jill BaborMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
Beate SchwerDepartment of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, USA bschwer@med.cornell.edu shumans@mskcc.org.
Stewart ShumanMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA bschwer@med.cornell.edu shumans@mskcc.org.
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI FRANCESCA M GANY · 1985 to 2026
$347.4M
Mechanisms of DNA and RNA TransactionsR35GM126945 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Stewart H Shuman · 2018 to 2026
$8.9M
Inositol pyrophosphate dynamics affect RNA 3'-processing/transcription terminationR01GM134021 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI BEATE SCHWER · 2019 to 2026
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Genetic suppression of precocious transcription termination identifies mutations in essential subunits of the fission yeast cleavage and polyadenylation machinery. · full record | Socratic