Evidence mapPaperPMID 40908149Full record

ReviewJournal of applied physiology (Bethesda, Md. : 1985)2025

Cardiovascular challenges of aging in a hotter environment: a narrative review.

Rachel M Cottle, S Tony Wolf, W Larry Kenney

Abstract readReview
In one paragraph

Review in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rachel M CottleDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, United States.ORCID 0000-0002-6567-9785
S Tony WolfDepartment of Kinesiology, University of Georgia, Athens, Georgia, United States.ORCID 0000-0002-6336-2143
W Larry KenneyDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, United States.ORCID 0000-0002-1326-8175

Funding

Psychosocial Determinants and Biological Pathways to Healthy Aging (Pathways)T32AG049676 · PENNSYLVANIA STATE UNIVERSITY, THE · 2025 to 2025
$10k
HHS | National Institutes of Health (NIH) AG067471HHS | NIH | National Institute on Aging (NIA) AG049676NIA NIH HHS R01 AG067471NIA NIH HHS T32 AG049676
6 · The paper itself

Abstract

The increase in duration, severity, and frequency of extreme heat will have a profound detrimental impact on human health, as extreme heat is the deadliest weather-related event around the world. At the same time, the population of older (>65 yr) adults is rapidly expanding. The exaggerated heat, coupled with an aging population, increases the number of people at risk during environmental extremes. During heat waves, cardiovascular events and complications secondary to elevated core temperatures are the leading cause of increased morbidity and mortality among older adults. Seminal work demonstrates an impaired cardiovascular response to elevated core and skin temperatures in older adults, resulting in an attenuated capacity to lose heat coupled with increased cardiac strain, in support of the epidemiological data. Here, we review the impact of heat stress on the aged cardiovascular system and highlight the question: "In what specific environments does an increased cardiovascular strain begin to occur in older adults?"

Indexed as

AgingCardiovascular DiseasesCardiovascular SystemHeat Stress DisordersHot TemperatureAgedBody Temperature RegulationHumansheart rateheat waveolder adults

Identifiers

PMID40908149
PMCPMC12481594

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.