Evidence mapPaperPMID 40908524Full record

ReviewMini reviews in medicinal chemistry2025

Current Developments in the Pharmacological Activities and Synthesis of Carbazole Derivatives.

Gersy Marie Joelle Oba, Rakesh Sahu, Kamal Shah, Deepika Paliwal, Ashok Kumar Sah, Aman Thakur

Abstract readReview
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In one paragraph

Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gersy Marie Joelle ObaDepartment of Pharmacy, School of Pharmacy, Sharda University, Greater Noida, 201310, India.ORCID 0009-0000-9653-328X
Rakesh SahuDepartment of Pharmacy, School of Pharmacy, Sharda University, Greater Noida, 201310, India.ORCID 0000-0002-2500-9277
Kamal ShahDepartment of Pharmaceutical Chemistry, Institute of Pharmaceutical Research, GLA University, Mathura, 281406, India.ORCID 0000-0003-2389-0563
Deepika PaliwalDepartment of Pharmaceutical Chemistry, School of Medical and Allied Sciences, Galgotias University, Greater Noida, 201310, India.ORCID 0000-0002-2444-1500
Ashok Kumar SahDepartment of Medical Laboratory Sciences, College of Applied and Health Sciences, A' Sharqiyah University, Ibra, Sultanate of Oman.ORCID 0000-0002-7762-4351
Aman ThakurAdarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh, Saharanpur, 247341, India.ORCID 0000-0002-4951-9474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing prevalence of multidrug resistance and its detrimental effects pose a significant threat to public health, which is one reason for the current interest in the introduction of novel agents. To combat this adverse effect and drug resistance, numerous drugs have been developed over time, and their safety is still being evaluated; derivatives or medications based on the carbazole moiety are one of the key contributors. Therefore, this review explores carbazole-based derivatives as possible drugs to treat Alzheimer's, diabetes, inflammation, cancer, and many more, along with their synthetic schemes, SARs, and activity. Some of the carbazole-based drugs available in the market and under clinical trials are also tabulated. By integrating this insight, describe how these compounds are being reinvented as targeted therapeutic agents. This comprehensive analysis is designed to guide researchers in developing next-generation drugs to address various challenges and leverage the unique pharmacological properties of carbazole-derived drugs.

Indexed as

Antineoplastic AgentsCarbazolesDrug DevelopmentAlzheimer DiseaseAnimalsDiabetes MellitusHumansInflammationMolecular StructureNeoplasmsAntineoplastic AgentscarbazoleCarbazolesanti-alzheimeranticancerantidiabeticanti-inflammatoryantithyroidcarbazoleSynthesistreatment.

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.