ArticleFrontiers in neurology2025
Predictors of futile recanalization after endovascular therapy in anterior circulation stroke with large core infarction.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: There is a lack of data to predict futile recanalization (FR) after endovascular treatment (EVT) in acute anterior circulation large vessel occlusion (ACLVO) with large core infarction. Methods: This analysis included patients from a national multicenter stroke registry (November 2021 to February 2023). Patients who achieved successful recanalization (expanded Thrombolysis in Cerebral Infarction [eTICI] score ≥2b) after EVT were categorized into two groups: meaningful recanalization (MR; 90-day modified Rankin scale [mRS] 0-3) and FR (mRS 4-6). Multivariate logistic regression was performed to identify independent predictors of FR. Results: Among 313 patients with successful recanalization, 171 (54.6%) experienced FR, and 142 (45.4%) achieved MR. Multivariate analysis showed that a higher baseline NIH Stroke Scale score ( Conclusion: In patients with ACLVO and large core infarction, age, hyperglycemia, baseline NIHSS, poor collaterals, and incomplete recanalization were independent predictors of FR. These findings may be used to guide treatment decisions and optimize management processes.
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