ReviewFood science & nutrition2025
Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review.
Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Phytochemicals in arthritis management: insight into pharmacodynamic potency with pharmacokinetic profile.Inflammopharmacology · 2026Review
- Modulation of Redox Balance by Phytochemicals: Implications for Cardiovascular Health.Nutrients · 2026Review
- The Protective Effect of Carvacrol Against Isoproterenol-Induced Cardiotoxicity in Rats.Medeniyet medical journal · 2026Article
- Triazole-(RSC advances · 2026Article
- A comprehensive review of ischemic heart disease: pathophysiology, current treatments, natural products-based therapies, and nanotherapeutics.Frontiers in pharmacology · 2026Review
- Fruit and vegetable consumption and metabolic syndrome in Chinese adults: a cross-sectional study.Frontiers in nutrition · 2026Article
- Influence of Aqueous, Ethanolic, and Hydroethanolic Extraction on Phytochemical Content and Cardiometabolic-Related Bioactivities of Four Cameroonian Spices.BioMed research international · 2026Article
- Phytochemicals: Principles and Practice.Biology · 2025Review
- Review
- Foodomics in Diabetes Management: A New Approach.Food science & nutrition · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease (CVD) is the leading cause of death worldwide and a major public health issue. According to recent World Health Organization (WHO) estimates, CVD causes approximately 17.9 million deaths annually, accounting for 32% of global mortality. Prevention strategies that are dependent on dietary and lifestyle changes are becoming increasingly popular despite advances in pharmaceutical treatments. There has been a growing interest in phytochemicals and bioactive compounds in plants, as well as their potential to aid cardiovascular health and reduce the risk of cardiovascular disease. However, there is no comprehensive synthesis of their mechanisms, clinical relevance, and bioavailability. This review attempted to fill this gap by evaluating the therapeutic value of phytochemicals for the prevention and management of CVD. Dietary sources and classifications of cardioprotective phytochemicals, including phytosterols, carotenoids, alkaloids, and polyphenols, are extensively discussed in this review. The article goes in-depth on how they act through many different functions, such as antioxidant, anti-inflammatory, lipid-modulating, and endothelial-protective activities. Beyond describing the relationship between phytochemicals and broader dietary trends and lifestyle patterns, this article addresses their influences on bioavailability, including food matrix effects and gut microbiota. This review highlights the therapeutic significance of phytochemicals and their possible incorporation into standard treatments based on epidemiological, clinical, and mechanistic studies. Finally, this highlighted the need for future studies to fully exploit phytochemicals in the prevention and treatment of CVD, as well as the current issues in this regard.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.