Evidence map›Paper›PMID 40909262›Full record

ArticleFrontiers in immunology2025

SFB flagellin mediates cell adhesion, endocytosis and immune regulation in germ-free mice.

Huahai Chen, Liu Wu, Xiongyu Cao, Zongyan Li, Renjun Zhu, Xiaojing Wang, Jun Li, Zuzhang Wei, Dengfeng Yang, Yeshi Yin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huahai ChenGuangxi Academy of Marine Sciences, Guangxi Academy of Sciences, Nanning, Guangxi, China.
Liu WuCollege of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China.
Xiongyu CaoCollege of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China.
Zongyan LiCollege of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China.
Renjun ZhuCollege of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China.
Xiaojing WangCollege of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China.
Jun LiGuangxi Veterinary Research Institute, Nanning, Guangxi, China.
Zuzhang WeiCollege of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China.
Dengfeng YangGuangxi Academy of Marine Sciences, Guangxi Academy of Sciences, Nanning, Guangxi, China.
Yeshi YinCollege of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Segmented filamentous bacteria (SFB) colonization dynamics are crucial for host immune regulation. Given this, the present study specifically examined the functions of SFB flagellin in bacterial adhesion, cellular internalization, and immune modulation. Methods: Results and discussion: The results of

Indexed as

Bacterial AdhesionEndocytosisFlagellinAnimalsCell AdhesionCell LineEscherichia coliGerm-Free LifeLactococcus lactisMiceMolecular Docking SimulationRatsTh17 CellsFlagellinbacterial adhesionendocytosisflagellingerm-free mousesegmented filamentous bacteriaTh17 cell differentiation

Identifiers

PMID40909262
PMCPMC12405183

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.