Evidence map›Paper›PMID 40909800›Full record

ArticleResearch square2025

Multimodal Approach to Intraventricular Hemorrhage Using Echocardiography, Near-Infrared Spectroscopy, and Electrical Cardiometry in Preterm Infants.

Aleksandra Hibner, Khang Tong, Lin Liu, Ana Morales, Shashank Sanjay, Henry Lee, Anup Katheria

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PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Aleksandra HibnerUCSD.ORCID 0009-0009-6815-5301
Khang TongUniversity of California, San Diego.
Lin LiuUniversity of California, San Diego.
Ana Morales
Shashank SanjaySharp Mary Birch Hospital for Women & Newborns.ORCID 0009-0000-8069-9242
Henry LeeUniversity of California San Diego.ORCID 0000-0001-8383-1720
Anup KatheriaSharp Mary Birch Hospital for Women & Newborns.ORCID 0000-0001-9352-0934

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
NCATS NIH HHS UL1 TR001442
6 · The paper itself

Abstract

objectiveTo investigate single versus combination hemodynamic parameters on intraventricular hemorrhage (IVH) or mortality in preterm infants. STUDY

designData from 482 infants under 32 weeks gestational age were analyzed, including cerebral oximetry, mean arterial pressure (MAP), cardiac output, and systemic blood flow within the first 24 h. Wilcoxon Rank-Sum and chi-squared tests compared variables. Multivariable logistic regression and receiver operator curve (ROC) analyses assessed predictive value.

resultsEach additional gestational week was associated with lower odds of IVH (OR=0.66; 95% CI: 0.57-0.75) and mortality (OR=0.56; 95% CI: 0.45-0.69). Adjusted for covariates, right ventricular output (RVO) was associated with reduced IVH odds (AOR=0.996; 95% CI: 0.991-0.999), and higher MAP with reduced mortality (AOR=0.81; 95% CI: 0.68-0.94). Average NIRS <74% in 24 h increased mortality risk (OR=4.16; 95% CI: 1.46-11.0; P=0.005).

conclusionSelect hemodynamic measures are associated with IVH and death. Combining factors did not enhance early risk prediction.

Identifiers

PMID40909800
PMCPMC12408022

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.