ReviewNeuropsychiatric disease and treatment2025
Efficacy of Acupuncture Therapy in Treating Non-Motor Symptoms of Parkinson's Disease: A Systematic Review and Network Meta-Analysis.
Review in Neuropsychiatric disease and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Recently, research on the management of Parkinson's disease (PD), particularly non-motor symptoms (NMS), has been increasingly reported. This systematic review and network meta-analysis (NMA) aimed to evaluate the efficacy of acupuncture interventions for NMS in PD patients to identify the most effective strategy. Methods: Randomized controlled trials (RCTs) on acupuncture for NMS in PD were retrieved up to July 31, 2024, across eight databases: PubMed, Embase (OVID), Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, VIP Database, and Wanfang Database. The quality of the included studies was assessed using the Cochrane handbook for systematic reviews. Results: 77 RCTs were included, involving 5538 PD patients. The NMA indicated that acupuncture_training_usual ([SUCRA] = 84.18%) was the best intervention for improving the anxiety state of PD patients. Abdominal_acupuncture_usual (94.15%) was a preferred intervention for improving the depressive state. Scalp_acupuncture_usual (99.98%) and Scalp_electroacupuncture (94.28%) can significantly improve the sleep quality of PD patients. Heat_sensitive_moxibustion_usual (94.65%) and Warm_acupuncture_moxibustion_usual (99.995%) can significantly improve the quality of life of PD patients. Acupuncture_usual (94.02%) may be considered a promising intervention for improving the psychological, emotional and cognitive functions. Additionally, shallow_acupuncture_usual (99.17%) was the safest option. Notably, acupuncture_moxibustion (98.24%) was the most effective intervention involving the largest number of participants. Conclusion: This analysis identifies the most effective acupuncture interventions for improving NMS in PD patients, including anxiety, depression, sleep quality, and overall quality of life, as well as additional benefits in pain management and gastrointestinal function. Future large-scale RCTs are needed to confirm these findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.