Evidence map›Paper›PMID 40910551›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2026

Identifying Latent Classes of Dual Cigarette/ENDS Users Based on Motivations for ENDS Use: Product Substitution Versus Complementary Use.

Lauren R Pacek, Ollie Ganz, Dana Rubenstein, Patrick V Barnwell, F Joseph McClernon

Abstract read
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Lauren R PacekRutgers Institute for Nicotine & Tobacco Studies, Rutgers Biomedical and Health Sciences, New Brunswick, NJ, USA.ORCID 0000-0002-1412-1765
Ollie GanzRutgers Institute for Nicotine & Tobacco Studies, Rutgers Biomedical and Health Sciences, New Brunswick, NJ, USA.
Dana RubensteinDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.ORCID 0000-0003-4103-9641
Patrick V BarnwellRutgers Institute for Nicotine & Tobacco Studies, Rutgers Biomedical and Health Sciences, New Brunswick, NJ, USA.
F Joseph McClernonDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.

Funding

Tobacco Industry Marketing CoreU54CA229973 · NCI · UNIVERSITY OF PENNSYLVANIA · PI WACKOWSKI, OLIVIA · 2018 to 2022
$18.8M
Rutgers Center of Excellence in Rapid Surveillance of TobaccoU01CA278695 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI CRISTINE D DELNEVO, Ollie Ganz · 2023 to 2026
$14.0M
NCI NIH HHS U01 CA278695NCI NIH HHS U54 CA229973
6 · The paper itself

Abstract

introductionThe aim of this study was to empirically identify subgroups of dual cigarette and electronic nicotine delivery systems (ENDS) product users based on their motivations for ENDS use.

methodsData came from n = 713 adult dual cigarette/ENDS users in the Population Assessment of Tobacco and Health Wave 6 public use data file. We used latent class analysis to identify qualitatively different subgroups within the sample and applied logistic regression to assess correlates of latent class membership.

resultsWe identified two latent classes: "Substituters" (62.81%) and Complementers (37.19%). Classes were primarily distinguished by Substituters reporting a higher probability of using ENDS to cut down on (97.99%) or quit (86.12%) cigarette smoking; the converse was true for Complementers (16.95%; 3.17%, respectively). Compared to Substituters, Complementers (aOR = 0.87, 95% CI = 0.81 to 0.96) expressed less interest in smoking cessation. Moreover, Complementers were less likely to have made a past-year smoking quit attempt (aOR = 0.46, 95% CI = 0.27 to 0.77) and more likely to smoke the same number of cigarettes as usual (aOR = 3.62, 95% CI = 2.04 to 6.42) or more cigarettes than usual (aOR = 5.96, 95% CI = 1.92 to 18.51) on days when they both smoked and vaped than were Substituters. No sociodemographic differences were observed.

conclusionsWe identified distinct latent classes of dual cigarette/ENDS users, predominantly differentiated based on their reported probabilities of using ENDS to assist in quitting or cutting down on cigarette smoking. Findings that class membership is associated with interest in quitting and quit attempts have significant health, treatment, and study design implications. IMPLICATIONS: The identification of distinct classes of dual cigarette/ENDS users based on their motivations for ENDS use and differential associations between class membership and tobacco use characteristics has a number of implications. Class membership may affect cessation treatment approaches and has significant implications for scientific study design.

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsMotivationSmoking CessationTobacco ProductsVapingAdolescentAdultFemaleHumansLatent Class AnalysisMaleMiddle AgedYoung Adult

Identifiers

PMID40910551
PMCPMC12628351

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.