Evidence map›Paper›PMID 40910752›Full record

ArticleAnales del sistema sanitario de Navarra2025

Six Sigma research in healthcare is associated with global health, research and development indicators: A scientometrics study based on countries by income groups.

Estefany Romero-Freile, Darwin Ortiz-Cerchar, David A Hernández-Páez, Ornella Fiorillo-Moreno, Yelson Alejandro Picón-Jaimes, Tulia Beltrán-Venegas, Johana Galván-Barrios, Ivan David Lozada-Martinez

Abstract read
In one paragraph

Article in Anales del sistema sanitario de Navarra, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Estefany Romero-FreileUniversidad de la Costa. Barranquilla. Colombia.
Darwin Ortiz-CercharUniversidad de la Costa. Barranquilla. Colombia.
David A Hernández-PáezCenter for Meta-Research and Scientometrics in Biomedical Sciences. Barranquilla. Colombia.
Ornella Fiorillo-MorenoClínicas Iberoamérica y El Carmen. Barranquilla. Colombia.
Yelson Alejandro Picón-JaimesUniversitat Ramon Llull. Facultat de Ciències de la Salut Blanquerna. Barcelona. Spain.
Tulia Beltrán-VenegasUniversidad de la Costa. Barranquilla. Colombia.
Johana Galván-BarriosUniversidad de la Costa. Department of Health Sciences. Biomedical Scientometrics and Evidence-Based Research Unit. Barranquilla. Colombia.
Ivan David Lozada-MartinezUniversidad de la Costa. Department of Health Sciences. Biomedical Scientometrics and Evidence-Based Research Unit. Barranquilla. Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSix Sigma is widely implemented in healthcare to enhance efficiency, minimize medical errors, and improve patient safety. However, the global distribution and impact of Six Sigma research in healthcare remain underexplored. This study conducts a scientometrics analysis of Six Sigma research in healthcare, examining its association with global health, research, and development indicators across income groups. METHODOLOGY: A mixed-methods scientometrics study was employed, utilizing data from Scopus, PubMed, and other databases. Regression models and meta-analyses were applied to evaluate associations between Six Sigma research productivity and global health, research and development indicators. Publications were categorized by World Bank income groups, and bibliometric parameters such as impact were analysed.

resultsA total of 804 Six Sigma-related publications in healthcare were identified, with high-income countries contributing 70.8% of the total output. The number of publications was significantly associated with adult mortality reduction in high- and upper-middle income countries (p <0.01). Research and development expenditure showed a strong positive correlation with Six Sigma research output across all income groups. However, low-income countries exhibited minimal research activity, with no significant associations detected.

conclusionsSix Sigma research in healthcare is predominantly concentrated in high-income countries, with increasing but uneven growth in upper-middle and low-middle income countries. The limited engagement of low-income countries underscores a critical research gap.

Indexed as

BibliometricsBiomedical ResearchDelivery of Health CareGlobal HealthHealth Services ResearchTotal Quality ManagementDeveloped CountriesDeveloping CountriesHumansIncome

Identifiers

PMID40910752
PMCPMC12481413

What Socratic holds

Textmetadata
LicenceCC BY-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.