Evidence map›Paper›PMID 40911998›Full record

ArticleDrug and alcohol dependence2025

Medicaid prescription cap policies and acute care use and mortality among enrollees with opioid use disorder.

Patience M Dow, Christopher M Santostefano, Landon D Hughes, Elizabeth G Stettenbauer, Theresa I Shireman, Julie M Donohue, Lisa Peterson, Jaclyn M W Hughto

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patience M DowBrown University School of Public Health, Department of Health Services, Policy, and Practice, Providence, RI, USA. Electronic address: patience_dow@brown.edu.
Christopher M SantostefanoBrown University School of Public Health, Department of Health Services, Policy, and Practice, Providence, RI, USA.
Landon D HughesHarvard T. H. Chan School of Public Health, Department of Epidemiology, Boston, MA, USA; Harvard Pilgrim Health Care Institute, Department of Population Medicine, Boston, MA, USA.
Elizabeth G StettenbauerBrown University School of Public Health, Department of Health Services, Policy, and Practice, Providence, RI, USA.
Theresa I ShiremanBrown University School of Public Health, Department of Health Services, Policy, and Practice, Providence, RI, USA.
Julie M DonohueUniversity of Pittsburgh School of Public Health, Department of Health Policy and Management, Pittsburgh, PA, USA.
Lisa PetersonVICTA, Providence, RI, USA.
Jaclyn M W HughtoBrown University School of Public Health, Departments of Behavioral and Social Sciences and Epidemiology, Providence, RI, USA.

Funding

Impact of Prescription Caps on Health Outcomes in People Infected with HIVR01MH122301 · NIMH · BROWN UNIVERSITY · PI GALARRAGA, OMAR, SHIREMAN, THERESA I. · 2020 to 2024
$3.7M
Impact of Medicaid Prescription Cap Policies on Treatment Outcomes for Opioid Use Disorder: A National Mixed Methods StudyR01DA057979 · NIDA · BROWN UNIVERSITY · PI Patience Moyo Dow, Jaclyn White Hughto · 2023 to 2026
$3.0M
NIDA NIH HHS R01 DA057979NIMH NIH HHS R01 MH122301
6 · The paper itself

Abstract

backgroundTwelve state Medicaid programs limit the monthly number of covered prescriptions. Such cap policies may force enrollees to forego essential medications with important health consequences. We aimed to determine the impact of cap policies on acute care use and all-cause mortality among enrollees with opioid use disorder (OUD).

methodsUsing 2016-2019 T-MSIS Analytical Files, we propensity-score matched enrollees with OUD in 12 states with cap policies and 26 states without cap policies. Outcomes measured over 12 months included emergency department (ED) visits, hospitalization, and all-cause mortality and were analyzed via generalized linear regression models. We conducted subgroup analyses by use of medications for OUD (MOUD) and comorbidity level and sensitivity analyses to examine the role of cap policy characteristics.

resultsUnadjusted risks were 64.0 % vs. 62.5 % for ED visits, 27.6 % vs. 27.5 % for hospitalizations, and 3.2 % vs. 2.7 % for mortality in cap states and non-cap states, respectively. After adjustment, hospitalization risk was higher (RR=1.89, 99.5 %CI:1.13,3.16) in cap states than non-cap states whereas ED visits and mortality did not differ. There were largely no outcome differences by cap status in subgroups. Strict prescription limits allowing 3-4 prescriptions monthly (RR=1.90, 95 %CI:1.09,3.30) and lack of MOUD exemptions (RR=2.23, 95 %CI:1.32,3.78) were associated with increased hospitalization risk relative to non-cap states.

conclusionsMedicaid prescription cap policies were associated with increased hospitalization risk, but there were no differences in ED use or all-cause mortality. Cap policies may undermine the health of individuals with OUD and could be counterproductive to state efforts to curb Medicaid spending.

Indexed as

Health outcomesMedicaidOpioid use disorderPrescription limit policies

Identifiers

PMID40911998
PMCPMC12715808

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.