Evidence map›Paper›PMID 40912706›Full record

ArticleBMJ open2025

Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma (BLAASTT): protocol for a randomised controlled trial in adult trauma inpatients with painful rib fractures.

Rebecca E Kotcher, Matthew R Rosengart, Luca La Colla, Hsing-Hua Sylvia Lin, Keith M Vogt, Yan Xu, Matthew D Neal

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06626334 (Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06626334 naterminatednot on this map

Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma: A Randomized Controlled Trial in Adults With Rib Fractures

TypeinterventionalSponsorRebecca E Kotcher, MDRan2024 to 2026Enrolled27ConditionsRib Fractures, Pain, AcuteArmsBright Blue Light, Bright Full-Spectrum (White) Light, Usual Ambient Light
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rebecca E KotcherDepartment of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA kotcherre@upmc.edu.ORCID http://orcid.org/0000-0003-1061-2687
Matthew R RosengartDepartment of Surgery, Washington University in St Louis, St Louis, Missouri, USA.
Luca La CollaDepartment of Anesthesiology & Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Hsing-Hua Sylvia LinDepartment of Anesthesiology & Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Keith M VogtDepartment of Anesthesiology & Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Yan XuDepartment of Anesthesiology & Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Matthew D NealDepartment of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Research Training in Anesthesiology and Pain MedicineT32GM075770 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YAN XU · 2007 to 2026
$4.8M
NCATS NIH HHS UL1 TR001857NIGMS NIH HHS T32 GM075770
6 · The paper itself

Abstract

introductionBlue light (peak wavelength 442 nm) has been shown to modulate the immune response in preclinical models of intra-abdominal sepsis and pneumonia. METHODS AND ANALYSIS: This is a randomised controlled trial in which adult trauma inpatients ( ETHICS AND DISSEMINATION: Full ethical approval for this trial has been granted by the University of Pittsburgh Institutional Review Board. On study completion, results will be published in the peer-reviewed literature and at ClinicalTrials.gov. TRIAL REGISTRATION NUMBER: NCT06626334.

Indexed as

Pain ManagementPhototherapyRib FracturesThoracic InjuriesAdultBlue LightFemaleHumansMalePain MeasurementRandomized Controlled Trials as TopicDeliriumInflammationPain managementPulmonary DiseaseTrauma

Identifiers

PMID40912706
PMCPMC12414232

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.