Evidence map›Paper›PMID 40913258›Full record

ArticleAlcohol, clinical & experimental research2025

Understanding clustered behavioral risk factors among adults in the United States: A gender-specific analysis of alcohol and other substance use and obesity.

Won Kim Cook, Libo Li, William C Kerr, Priscilla Martinez

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Data-Driven Exploratory Analysis of the Alcohol-Harm Paradox in South-East Wales.International journal of environmental research and public health · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Won Kim CookAlcohol Research Group, Public Health Institute, Emeryville, California, USA.ORCID https://orcid.org/0000-0002-0390-297X
Libo LiAlcohol Research Group, Public Health Institute, Emeryville, California, USA.
William C KerrAlcohol Research Group, Public Health Institute, Emeryville, California, USA.ORCID https://orcid.org/0000-0001-6612-9200
Priscilla MartinezAlcohol Research Group, Public Health Institute, Emeryville, California, USA.ORCID https://orcid.org/0000-0002-6797-1632

Funding

TREND &STRUCTURE OF ALCOHOL DEPENDENCE--GENERAL POPULATION 1990 SURVEY DATAP50AA005595 · NIAAA · WESTERN CONSORTIUM FOR PUBLIC HEALTH · PI KERR, WILLIAM C. · 1985 to 2025
$34.1M
NIAAA NIH HHS P50 AA005595NIAAA NIH HHS P50AA005595
6 · The paper itself

Abstract

backgroundIndividuals who consume alcohol often use other drugs as well. Little is known about the clustering of heavy and binge drinking with the use of other substances (tobacco, cannabis, illicit drugs, and nonmedical prescription drugs). Overweight/obesity, highly prevalent in the United States (US) and an established health risk factor, may also cluster with them. We aimed to identify patterns of clustering of these behavioral risk factors and demographic and chronic disease profiles of individuals who show each pattern of clustering.

methodsLatent class analyses and multinomial and logistic regressions were conducted using a nationally representative sample of US adults (Analytic N = 214,505) from the 2015-2019 National Survey on Drug Use and Health. Demographic characteristics (age, race and ethnicity, education, and income) and chronic health conditions associated with each cluster of behavioral risk factors were examined, also adjusting for health insurance coverage and marital status. Analyses were stratified by gender.

resultsFour clusters with similar behavioral risk profiles were identified for both men and women: heavy-drinking-tobacco-some-cannabis-use-obese group, high-substance-use group, obese group, and relatively-healthy-lifestyle group. Additionally, heavy-drinking-tobacco-some-cannabis-use-overweight group and low-drinking-high-other-substance-use group for men and heavy-drinking-tobacco-some-cannabis-use group for women were identified. The high substance use group was more likely to be aged under 35. However, clusters featuring more commonly used substances (alcohol, tobacco, and, to a lesser degree, cannabis) were more likely to be midlife for men and to have higher income for both men and women. Clustered behavioral risk factors were positively associated with being White and having no college degree (with some exceptions) and negatively associated with self-rated health status and chronic conditions (except hypertension) for both sexes.

conclusionsClustered multisubstance use and obesity is a problem affecting a significant segment of the US population. Tailored multibehavior interventions are warranted.

Indexed as

Alcohol DrinkingObesitySubstance-Related DisordersAdolescentAdultAgedCluster AnalysisFemaleHumansMaleMiddle AgedRisk FactorsSex FactorsUnited StatesYoung Adultbinge drinkingheavy drinkingnonmedical prescription drug usesubstance usetobacco use

Identifiers

PMID40913258
PMCPMC13095351

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.