Evidence map›Paper›PMID 40914754›Full record

ReviewMolecular psychiatry2026

Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium.

Isabel K Schuurmans, Rosa H Mulder, Vilte Baltramonaityte, Alexandra Lahtinen, Fan Qiuyu, Leonardo Melo Rothmann, Marlene Staginnus, Jetro J Tuulari, S Alexandra Burt, Claudia Buss and 37 more

Abstract readReview
In one paragraph

Review in Molecular psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. The Evolving ADHD Phenotype in the Externalizing Context.The American journal of psychiatry · 2026
    Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

47 authors.

Isabel K SchuurmansDepartment of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID http://orcid.org/0000-0002-2312-4087
Rosa H MulderDepartment of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID http://orcid.org/0000-0002-2382-1704
Vilte BaltramonaityteDepartment of Psychology, University of Bath, Bath, UK.ORCID http://orcid.org/0000-0002-9776-735X
Alexandra LahtinenResearch Program in Systems Oncology, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0001-7179-2680
Fan QiuyuNational Institute of Health and Welfare, Department of Public Health and Welfare, Population Health Unit, Helsinki, Finland.
Leonardo Melo RothmannTranslational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Marlene StaginnusDepartment of Psychology, University of Bath, Bath, UK.ORCID http://orcid.org/0000-0002-4739-6271
Jetro J TuulariFinnBrain Birth Cohort Study, Turku Brain and Mind Center; Department of Clinical Medicine, University of Turku, Turku, Finland.
S Alexandra BurtMichigan State University, East Lansing, MI, USA.ORCID http://orcid.org/0000-0001-5538-7431
Claudia BussDevelopment, Health and Disease Research Program, University of California, Irvine, CA, USA.ORCID http://orcid.org/0000-0002-8738-3133
Jeffrey M CraigDeakin University, IMPACT - The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Geelong, VIC, Australia.
Kirsten A DonaldDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.
Johan G ErikssonInstitute for Human Development and Potential (IHDP), Agency for Science Technology and Research (A*STAR), Singapore, Singapore.
Janine F FelixThe Generation R Study Group, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID http://orcid.org/0000-0002-9801-5774
Tom P FreemanDepartment of Psychology, University of Bath, Bath, UK.
Rodrigo Grassi-OliveiraTranslational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0001-9911-5921
Anke HuelsDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-6005-417X
Luke W HydeDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-5947-7896
Scott A JonesCenter for Mental Health Innovation, Oregon Health & Science University, Portland, OR, USA.
Hasse KarlssonFinnBrain Birth Cohort Study, Turku Brain and Mind Center; Department of Clinical Medicine, University of Turku, Turku, Finland.
Linnea KarlssonFinnBrain Birth Cohort Study, Turku Brain and Mind Center; Department of Clinical Medicine, University of Turku, Turku, Finland.ORCID http://orcid.org/0000-0002-4725-0176
Nastassja KoenNeuroscience Institute, University of Cape Town, Cape Town, South Africa.
Will LawnDepartment of Psychology, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-0143-2724
Colter MitchellInstitute for Social Research, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0001-9560-1199
Christopher S MonkDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0001-9391-4669
Michael A MooneyCenter for Mental Health Innovation, Oregon Health & Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0003-1372-8722
Ryan MuetzelDepartment of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID http://orcid.org/0000-0003-3215-1287
Joel T NiggCenter for Mental Health Innovation, Oregon Health & Science University, Portland, OR, USA.
Síntia Iole Nogueira BelangeroFederal University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-2419-4351
Daniel NottermanDepartment of Molecular Biology, Princeton University, Princeton, NJ, USA.
Yi Ying OngDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0003-3072-765X
Tom O'ConnorUniversity of Rochester Medical Center, Departments of Psychiatry, Psychology, Neuroscience, and Obstetrics and Gynecology, Rochester, NY, USA.
Kieran J O'DonnellYale Child Study Center, Yale School of Medicine, New Haven, CT, USA.
Pedro Mario PanFederal University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-1943-6520
Tiina PaunioNational Institute of Health and Welfare, Department of Public Health and Welfare, Population Health Unit, Helsinki, Finland.ORCID http://orcid.org/0000-0002-5560-0666
Peter RyabininCenter for Mental Health Innovation, Oregon Health & Science University, Portland, OR, USA.
Richard SafferyMurdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-9510-4181
Giovanni A SalumDepartment of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Marc SealDepartment of Paediatrics, University of Melbourne, Royal Children's Hospital, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-8396-140X
Tim J SilkDevelopmental Imaging, Murdoch Children's Research Institute, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-7290-512X
Dan J SteinSAMRC Unit on Risk and Resilience in Mental Disorders, Cape Town, South Africa.ORCID http://orcid.org/0000-0001-7218-7810
Ai Peng TanInstitute for Human Development and Potential (IHDP), Agency for Science Technology and Research (A*STAR), Singapore, Singapore.ORCID http://orcid.org/0000-0001-7660-6322
Ai Ling TehInstitute for Human Development and Potential (IHDP), Agency for Science Technology and Research (A*STAR), Singapore, Singapore.
Dennis WangInstitute for Human Development and Potential (IHDP), Agency for Science Technology and Research (A*STAR), Singapore, Singapore.
Heather ZarDepartment of Paediatrics & Child Health, Red Cross Children's Hospital and SA-MRC Unit on Child & Adolescent Health, University of Cape Town, Cape Town, South Africa.
Esther Walton *Department of Psychology, University of Bath, Bath, UK. E.Walton@bath.ac.uk.ORCID http://orcid.org/0000-0002-0935-2200
Charlotte A M Cecil *Department of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands. c.cecil@erasmusmc.nl.ORCID http://orcid.org/0000-0002-2389-5922

Funding

Fragile Families and the Transition to AdulthoodR01HD036916 · NICHD · PRINCETON UNIVERSITY · PI Kathryn Edin, Jane Waldfogel · 1999 to 2026
$46.3M
Cross-Cultural Assessment of FASDU24AA014811 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY · 2003 to 2026
$13.1M
The Fragile Families Cardiovascular Health Follow Up StudyR01HL149869 · NHLBI · PRINCETON UNIVERSITY · PI LLOYD-JONES, DONALD M, NOTTERMAN, DANIEL A. · 2020 to 2023
$11.9M
COVID-19 supplement to a computational examination of threat and reward constructs in a predominantly low-income, longitudinal sample at increased risk for internalizing disordersR01MH121079 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HYDE, LUKE WILLIAMSON, MITCHELL, COLTER M.S. · 2019 to 2024
$7.2M
ADHD heterogeneity, mechanisms, and risk profileR37MH059105 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI NIGG, JOEL T · 2014 to 2023
$7.0M
Reciprocal Genetic-Environmental Interactions During Childhood and AdolescenceR01HD076592 · NICHD · PRINCETON UNIVERSITY · PI NOTTERMAN, DANIEL A. · 2013 to 2023
$6.8M
Childhood adversity, DNA methylation, and risk for depression: A longitudinal study of sensitive periods in developmentR01MH113930 · NIMH · PURDUE UNIVERSITY · PI Erin Cathleen Dunn · 2017 to 2026
$6.6M
Epigenetic Mediation of Adverse Social Context on Stress Response, Socioemotional Development, and Health in a Population-based Study of Minority and Low SES Children and AdolescentsR01MD011716 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MITCHELL, COLTER M.S. · 2017 to 2022
$4.6M
Tracking and Prediction of Early Brain-Face Biomarkers of Prenatal Alcohol Exposure from Neonates to ChildrenR01AA026834 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Kirsty Donald, Shantanu H. Joshi · 2018 to 2026
$3.8M
Brain trajectories in ADHDR01MH115357 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI FAIR, DAMIEN A, NIGG, JOEL T · 2017 to 2021
$3.8M
Mechanisms underlying resilience to neighborhood disadvantage (Administrative Supplement)UH3MH114249 · NIMH · MICHIGAN STATE UNIVERSITY · PI BURT, S. ALEXANDRA, HYDE, LUKE WILLIAMSON · 2018 to 2022
$3.5M
EMA Assessment of Biobehavioral Processes in Human PregnancyR01HD060628 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI WADHWA, PATHIK D · 2010 to 2014
$3.4M
NHLBI NIH HHS R01 HL149869NIAAA NIH HHS R01 AA026834NIAAA NIH HHS R21 AA023887NIAAA NIH HHS U24 AA014811NICHD NIH HHS R01 HD036916NICHD NIH HHS R01 HD060628NICHD NIH HHS R01 HD066040NICHD NIH HHS R01 HD068437NICHD NIH HHS R01 HD076592NICHD NIH HHS R01 HD093334NICHD NIH HHS R01 HD104297NIMHD NIH HHS R01 MD011716NIMHD NIH HHS R01 MD017387NIMH NIH HHS R01 MH081813NIMH NIH HHS R01 MH099064NIMH NIH HHS R01 MH103761NIMH NIH HHS R01 MH113930NIMH NIH HHS R01 MH115357NIMH NIH HHS R01 MH121079NIMH NIH HHS R01 MH131685NIMH NIH HHS R37 MH059105NIMH NIH HHS UH3 MH114249Wellcome Trust
6 · The paper itself

Abstract

Epigenetic processes, such as DNA methylation, show potential as biological markers and mechanisms underlying gene-environment interplay in the prediction of mental health and other brain-based phenotypes. However, little is known about how peripheral epigenetic patterns relate to individual differences in the brain itself. An increasingly popular approach to address this is by combining epigenetic and neuroimaging data; yet, research in this area is almost entirely comprised of cross-sectional studies in adults. To bridge this gap, we established the Methylation, Imaging and NeuroDevelopment (MIND) Consortium, which aims to bring a developmental focus to the emerging field of Neuroimaging Epigenetics by (i) promoting collaborative, adequately powered developmental research via multi-cohort analyses; (ii) increasing scientific rigor through the establishment of shared pipelines and open science practices; and (iii) advancing our understanding of DNA methylation-brain dynamics at different developmental periods (from birth to emerging adulthood), by leveraging data from prospective, longitudinal pediatric studies. MIND currently integrates 16 cohorts worldwide, comprising (repeated) measures of DNA methylation in peripheral tissues (blood, buccal cells, and saliva) and neuroimaging by magnetic resonance imaging across up to five time points over a period of up to 21 years (N

Indexed as

DNA MethylationAdolescentAdultBrainChildChild, PreschoolCohort StudiesCross-Sectional StudiesEpigenesis, GeneticEpigenomicsFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleNeurodevelopmental Disorders

Identifiers

PMID40914754
PMCPMC12514860

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.