Trial reportJournal of the American Geriatrics Society2025
Multi-Component Prehabilitation Program for Older Adults Undergoing Major Elective Surgery: A Pilot and Feasibility Study.
Trial report in Journal of the American Geriatrics Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05752474 (Multi-Component Prehabilitation Program for High-Risk Older Adults Undergoing Major Elective Surgery), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multi-Component Prehabilitation Program for High-Risk Older Adults Undergoing Major Elective Surgery: A Pilot and Feasibility Study
Who cites it
1 citing paper in PubMed.
- Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
backgroundPrehabilitation may help older adults recover after surgery, yet adherence has been variable. We assessed the feasibility of a multi-component prehabilitation program.
methodsThis single-arm trial was conducted at an academic medical center to test the feasibility of an individualized prehabilitation program before major surgery. The program consisted of twice-weekly physical therapy, weekly dietician consultations with daily protein supplementation, and weekly group meditation for 3-4 weeks. The primary outcome was adherence, as measured by the proportion of completed sessions. Secondary outcomes included changes in gait speed, chair stands, and grip strength after intervention and Patient-Reported Outcomes Measurement Information System (PROMIS)-Physical Function scores at 90 days post-surgery.
resultsOf 95 eligible patients, 30 (31.6%) were enrolled (mean [SD] age, 75.3 [6.6] years; 12 [40.0%] women; 19 cardiac and 11 non-cardiac procedures) and 28 began the intervention. Adherence was 91.3% (190/208 sessions completed) for physical therapy, 76.9% (80/104 sessions completed) for dietician consultation, and 68.3% (71/104 sessions completed) for meditation, with 67.9% of the participants completing at least 50% of each component. Among 25 participants (89.3%) who completed the intervention, mean walking speed increased (0.2 m/s; 95% CI: 0.0-0.4), and mean time to complete 5 chair stands decreased (3.4 s; 95% CI: -6.9 to 0.0), but mean grip strength did not change significantly (1.6 kg; 95% CI: -2.1 to 5.3). Among 22 out of 23 participants (95.7%) who underwent surgery, the mean PROMIS-Physical Function score improved by 4.4 points (95% CI: 3.0-5.9) at 90 days post-surgery compared to baseline. Adverse events included gastrointestinal discomforts (3 events), musculoskeletal pain (3 events), and dizziness (1 event).
conclusionsThis study demonstrates the feasibility of multicomponent prehabilitation in older patients scheduled for major elective surgery.
trial registrationNCT05752474.
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