Evidence mapPaperPMID 40916528Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2025

[Elevated advanced glycation endproducts is a risk factor for stenosis after primary arteriovenous fistula surgery].

Tianhong Li, Xinfang Qin, Lili Wei, Huixin Bi

Abstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Tianhong LiDepartment of Nephrology, First Affiliated Hospital of Guilin Medical University, Guilin 541000, China.
Xinfang QinDepartment of Nephrology, First Affiliated Hospital of Guilin Medical University, Guilin 541000, China.
Lili WeiDepartment of Nephrology, First Affiliated Hospital of Guilin Medical University, Guilin 541000, China.
Huixin BiDepartment of Nephrology, First Affiliated Hospital of Guilin Medical University, Guilin 541000, China.

Funding

National Natural Science Foundation of China 81960679
6 · The paper itself

Abstract

objectivesTo investigate the effect of serum advanced glycation endproducts (AGEs) on stenosis after first autologous arteriovenous fistula (AVF) in patients with end-stage renal disease (ESRD).

methodsPatients with ESRD undergoing standard native arteriovenous fistula (AVF) for the first time in the Department of Nephrology, Affiliated Hospital of Guilin Medical University from February to June 2022 were prospectively enrolled. The preoperative general data, clinical examination results and ultrasound data of the operated limbs were collected. The patients with and without stenosis within 2 months after the operation were compared for preoperative serum AGEs levels detected using ELISA and the clinical parameters. Logistic regression analysis was used to analyze the independent risk factors of AVF stenosis, and the sensitivity and specificity of AGEs for predicting postoperative stenosis were analyzed using receiver-operating characteristic (ROC) curve.

resultsOf the 94 patients enrolled, 34 had postoperative arteriovenous stenosis and 60 had no stenosis. The number of diabetic patients differed significantly between stenosis group and non-stenosis group (

conclusionsElevated serum AGEs level is an independent risk factor for postoperative AVF stenosis, and its combination with fibrinogen has a better efficacy for predicting postoperative AVF stenosis.

Indexed as

Arteriovenous Shunt, SurgicalGlycation End Products, AdvancedKidney Failure, ChronicPostoperative ComplicationsAdultAgedConstriction, PathologicFemaleHumansMaleMiddle AgedProspective StudiesRenal DialysisRisk FactorsROC CurveGlycation End Products, Advancedadvanced glycation end productsarteriovenous fistula stenosisend-stage renal diseasefibrinogen

Identifiers

PMID40916528
PMCPMC12415564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.