ArticleJournal of veterinary internal medicine
Plasma Arginine Vasopressin and Serum Copeptin Concentrations at Rest and After Osmotic- and Non-Osmotic-Based Stimulation Tests in Dogs.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Plasma Arginine Vasopressin and Serum Copeptin Concentrations at Rest and After Osmotic- and Non-Osmotic-Based Stimulation Tests in Dogs.Journal of veterinary internal medicineArticle
- Presumed partial aplasia of the hypothalamus and pituitary gland causing central diabetes insipidus in an adult cat.JFMS open reportsArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSerum copeptin (sCoP) is used as a surrogate for plasma arginine vasopressin (pAVP) measurement in humans.
objectiveTo measure pAVP and sCoP at rest and after osmotic- and non-osmotic stimulation testing in dogs. ANIMALS: Eight young castrated/spayed healthy research Beagles, eight young intact dogs, and eight old neutered healthy client-owned dogs.
methodsIn this prospective longitudinal study, pAVP and sCoP were measured under iso-(baseline), hypo-(water load followed by intravenous administration of desmopressin [WLT]), and hyper-(water deprivation test [WDT]) osmolar conditions assessed by measured plasma osmolality (pOsm
resultsBaseline sCoP had wide inter-individual variations. Mean [range] FpAVP and FsCoP at the end of WDT were +110% [+80; +142] and +18% [+0.4; +38] compared to baseline, respectively. Mean [range] FpAVP after water load and FsCoP after water load followed by desmopressin administration were -22% [-48; -0.5] and -29% [-39; -14] compared to baseline, respectively. Both FpAVP and FsCoP were strongly correlated to FpOsm CONCLUSION AND CLINICAL IMPORTANCE: Serum CoP could be used as a surrogate for pAVP measurement in healthy dogs.
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Registered trials
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