Evidence mapPaperPMID 40916812Full record

ReviewZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2025

Mechanism of post cardiac arrest syndrome based on animal models of cardiac arrest.

Halidan Abudu, Yiping Wang, Kang He, Ziquan Liu, Liqiong Guo, Jinrui Dong, Ailijiang Kadeer, Guowu Xu, Yanqing Liu, Xiangyan Meng and 3 more

Abstract readReview
In one paragraph

Review in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Halidan AbuduScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072. halida_abudou@126.com.
Yiping WangScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072.
Kang HeBioengineering College of Chongqing University, Chongqing 400044.
Ziquan LiuScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072.
Liqiong GuoScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072.
Jinrui DongScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072.
Ailijiang KadeerDepartment of Medical Oncology, First Affiliated Hospital of Bengbu Medical University, Bengbu 233030.
Guowu XuDepartment of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.
Yanqing LiuScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072.
Xiangyan MengScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072.
Jinxia CaiScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072.
Yongmao LiScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072.
Haojun FanScool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072. haojunfan86@163.com.

Funding

the National Key Research and Development Program 2021YFC3002205the Postgraduate Research and Innovation Program of Tianjin Municipal Education Commission 2022BKY113This is an open access article under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International CC BY-NC-ND 4.0 and //creativecommons.org/licenses/by-nc-nd/4.0/
6 · The paper itself

Abstract

Cardiac arrest (CA) is a critical condition in the field of cardiovascular medicine. Despite successful resuscitation, patients continue to have a high mortality rate, largely due to post CA syndrome (PCAS). However, the injury and pathophysiological mechanisms underlying PCAS remain unclear. Experimental animal models are valuable tools for exploring the etiology, pathogenesis, and potential interventions for CA and PCAS. Current CA animal models include electrical induction of ventricular fibrillation (VF), myocardial infarction, high potassium, asphyxia, and hemorrhagic shock. Although these models do not fully replicate the complexity of clinical CA, the mechanistic insights they provide remain highly relevant, including post-CA brain injury (PCABI), post-CA myocardial dysfunction (PAMD), systemic ischaemia/reperfusion injury (IRI), and the persistent precipitating pathology. Summarizing the methods of establishing CA models, the challenges encountered in the modeling process, and the mechanisms of PCAS can provide a foundation for developing standardized CA modeling protocols.

Indexed as

Disease Models, AnimalHeart ArrestPost-Cardiac Arrest SyndromeAnimalsHumansVentricular Fibrillationanimal modelcardiac arrestmodeling methodpathophysiologypost cardiac arrest syndrome

Identifiers

PMID40916812
PMCPMC12406098

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.