Evidence map›Paper›PMID 40917246›Full record

ArticleFrontiers in psychiatry2025

Cognitive functions among Saudi patients with methamphetamine and cannabis use disorder.

Shrief Y Afifi, Abdulkhaliq S S Alghamdi, Ahmed Sallam, Mohammed S A Almuqahwi, Ibrahim A Al-Sayegh, Farah M O Alzahrani, Amerah N Al-Zain Al-Dain, Afrah N Al-Zain Al-Deen, Abeer A ALabdulhadi, Moatazbellah I Ali

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shrief Y AfifiNeuropsychiatry Department, Okasha Institute of Psychiatry, Ain Shams University, Cairo, Egypt.
Abdulkhaliq S S AlghamdiDepartment of Addiction, Erada Complex and Mental Health in Dammam, Easter Health Cluster, Dammam, Saudi Arabia.
Ahmed SallamDepartment of Addiction, Erada Complex and Mental Health in Dammam, Easter Health Cluster, Dammam, Saudi Arabia.
Mohammed S A AlmuqahwiDepartment of Addiction, Erada Complex and Mental Health in Dammam, Easter Health Cluster, Dammam, Saudi Arabia.
Ibrahim A Al-SayeghDepartment of Addiction, Erada Complex and Mental Health in Dammam, Easter Health Cluster, Dammam, Saudi Arabia.
Farah M O AlzahraniDepartment of Addiction, Erada Complex and Mental Health in Dammam, Easter Health Cluster, Dammam, Saudi Arabia.
Amerah N Al-Zain Al-DainDepartment of Addiction, Erada Complex and Mental Health in Dammam, Easter Health Cluster, Dammam, Saudi Arabia.
Afrah N Al-Zain Al-DeenDepartment of Addiction, Erada Complex and Mental Health in Dammam, Easter Health Cluster, Dammam, Saudi Arabia.
Abeer A ALabdulhadiDepartment of Addiction, Erada Complex and Mental Health in Dammam, Easter Health Cluster, Dammam, Saudi Arabia.
Moatazbellah I AliNeuropsychiatry Department, Okasha Institute of Psychiatry, Ain Shams University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methamphetamine use disorder (MUD) is linked to a variety of cognitive and neuropsychiatric deficits. One of the illegal substances that is most frequently abused is cannabis. The general consensus is that both recreational cannabis and methamphetamine use result in a wide spectrum of severe cognitive impairments, although there have been questions raised regarding conclusions derived from published material. The purpose of this work is to describe how cannabis and methamphetamine use disorder affects human cognition in a group of Saudi patients. Methods: A cross-sectional observational study has been done at Erada Complex and Mental Health, Dammam, KSA. The study included three groups: the first group consisted of individuals who have methamphetamine use disorder, the second group included individuals with disorders related to cannabis use disorder, and the third group comprised healthy persons as a control group. The patients' demographic information has been gathered. Urine toxicological testing for cannabis and methamphetamine has been used to evaluate recent drug use. We employed SCID-I [a semi-structured interview to diagnose mental illnesses using the standards set out in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)] to rule out other mental illnesses and confirm cannabis and methamphetamine use disorder. At the time of interview, all individuals underwent cognitive evaluations using standardized neuropsychological tests for screening by MoCA, followed by Wechsler Memory Scale and Stroop's test for executive function. Results: A significant difference could be seen in all aspects of cognitive functions among patients and controls upon application of MoCA, Wechsler Memory Scale, and Stroop tests. On the other hand, there was statistical significance in most of the features among patients with either methamphetamine or cannabis use disorder using the same scales. Conclusion: Cognitive functions were affected in the studied group of Saudi patients who suffer from cannabis and methamphetamine use disorder compared to the control group, with those who were diagnosed with methamphetamine use disorder having greater effects on cognitive functions than those who were diagnosed with cannabis use disorder.

Indexed as

cannabiscognitive functionsmethamphetamineMoCAStroop testWASI

Identifiers

PMID40917246
PMCPMC12411442

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.