ArticleOphthalmology science
Evaluation of Retinal Edema in Nonproliferative Diabetic Retinopathy Using Widefield Swept-Source OCT.
Article in Ophthalmology science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Phenotype-driven management of diabetic macular edema: multimodal imaging biomarkers and individualized therapy.Frontiers in medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study evaluates retinal volume in the macula and peripheral retina in patients with nonproliferative diabetic retinopathy (NPDR), with and without diabetic macular edema (DME), using widefield swept-source OCT (SS-OCT). Design: Retrospective observational study. Participants: A total of 98 eyes were included: 30 from patients with NPDR without DME (DME-), 38 from patients with NPDR with DME (DME+), and 30 from age- and sex-matched healthy controls. Methods: OCT examinations used SS-OCT (Xephilio OCT-S1; Canon) to capture 23 × 20 mm (1024 × 128 A-scans) cube images. Retinal volume was calculated for each sector in a 9-sector grid defined by concentric circles (1 mm, 6 mm, and 20 mm in diameter) centered on the fovea and divided into four quadrants: superior, inferior, nasal, and temporal. The macular region was defined within a 6-mm diameter, whereas the peripheral retina spanned 6 mm to 20 mm. Main Outcome Measures: Macular and peripheral retinal volumes measured from SS-OCT images in each group. Results: A total of 98 eyes were analyzed (control: 30; DME-: 30; DME+: 38). Macular retinal volume was 8.46 ± 0.49 mm Conclusions: Our findings indicate that retinal volume increases in both macular and peripheral regions in DME, particularly as NPDR severity progresses. Financial Disclosures: The author has no/the authors have no proprietary or commercial interest in any materials discussed in this article.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.