Evidence mapPaperPMID 40917496Full record

ReviewResearch (Washington, D.C.)2025

Focusing on Microenvironmental Disturbance to Potentiate Reparative Ability of Neural Stem Cell After Stroke.

Hongfei Ge, Haomiao Wang, Rong Hu

Abstract readReview
In one paragraph

Review in Research (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hongfei GeDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), 400038 Chongqing, China.
Haomiao WangDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), 400038 Chongqing, China.
Rong HuDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), 400038 Chongqing, China.ORCID https://orcid.org/0000-0002-3916-186X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke (IS), a common neurological disease, lacks satisfactory treatments worldwide. Neural stem cell (NSC) therapy is a promising strategy for stroke, while microenvironmental disturbance, including but not limited to acidosis, oxidative stress, and excessive neuroinflammation, restricts the therapeutic potential of endogenous and exogenous NSC post-IS. The present study introduces the effect of common disturbance on NSC and the underlying mechanism to screen out feasible methods aiming to potentiate the reparative capacity of NSC following IS.

Identifiers

PMID40917496
PMCPMC12411917

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.