ReviewMetabolism open2025
Supplementary use of natural products in managing dumping syndrome: Exploring dietary and phytochemical interventions.
Review in Metabolism open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dumping syndrome (DS) is a known complication following bariatric surgery, caused by rapid gastric emptying into the small intestine. It presents in two forms: early dumping, with gastrointestinal and vasomotor symptoms occurring within 30-60 min after meals; and late dumping, which arises 1-3 h postprandially due to reactive hypoglycaemia. Standard management includes dietary changes and medications, but tolerability and long-term efficacy are variable. Recently, interest has grown in using natural products and nutritional compounds as adjuncts or alternatives. Fibre-rich foods, sugar substitutes, and medicinal plants may delay gastric emptying, reduce glucose spikes, or modulate gut hormones such as GLP-1 and GIP. Several phytochemicals, polyphenols, flavonoids, alkaloids, and terpenoids have demonstrated promise in reducing DS symptoms, especially in late dumping. Functional foods may enhance satiety, slow carbohydrate absorption, and improve glycaemic control. Although most data are from preclinical or limited clinical studies, natural compounds appear to be well-tolerated and safe, offering potential advantages over standard pharmacological agents. This review summarises emerging evidence on the role of natural products in managing DS, their mechanisms of action, and their clinical relevance in post-bariatric care. The findings aim to support translational metabolic care and provide practical guidance for clinicians and dietitians managing DS in diverse patient populations.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.