Evidence map›Paper›PMID 40917652›Full record

ArticleBioinformatics advances2025

A graph attention-based deep learning network for predicting biotech-small-molecule drug interactions.

Fatemeh Nasiri, Mohsen Hooshmand

Abstract read
In one paragraph

Article in Bioinformatics advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fatemeh NasiriDepartment of Computer Science and Information Technology, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, 45137-66731, Iran.
Mohsen HooshmandDepartment of Computer Science and Information Technology, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, 45137-66731, Iran.ORCID https://orcid.org/0000-0002-2934-2675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivation: The increasing demand for effective drug combinations has made drug-drug interaction prediction a critical task in modern pharmacology. While most existing research focuses on small-molecule drugs, the role of biotech drugs in complex disease treatments remains relatively unexplored. Biotech drugs, derived from biological sources, have unique molecular structures that differ significantly from those of small molecules, making their interactions more challenging to predict. Results: This study introduces a novel graph attention network Availability and implementation: The datasets and source code of this study are available in the GitHub repository: https://github.com/BioinformaticsIASBS/BSI-Net.

Identifiers

PMID40917652
PMCPMC12408249

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.