Evidence map›Paper›PMID 40918368›Full record

ArticleACS omega2025

Ultrasound Imaging and Machine Learning for Nondestructive Sensing in Bioreactors.

Mary Serpe, Caleb Lee, Reid Povinelli, Richard Thyden, Luke Perreault, Keshi He, Glenn R Gaudette, Antonio C F Dos Santos, Bryan J Ranger

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mary SerpeDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.
Caleb LeeDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.
Reid PovinelliDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.
Richard ThydenDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.
Luke PerreaultDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.
Keshi HeDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.
Glenn R GaudetteDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.
Antonio C F Dos SantosDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.
Bryan J RangerDepartment of Engineering, Boston College, 245 Beacon Street, Chestnut Hill, Massachusetts 02446, United States.ORCID https://orcid.org/0000-0002-4774-3587

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advancement of cell therapy and cellular agriculture underscores the need for noninvasive, cost-effective methods for continuous monitoring of large-scale cell production. Bioreactors, designed to mimic physiological conditions to facilitate cell growth, require reliable quality control measures. This study investigates the potential of ultrasound technology to characterize cellular growth and decellularization in spinach scaffolds. Ultrasound images were acquired of fresh spinach leaves, decellularized leaves, and leaves with cells seeded in defined cloning well regions on decellularized leaves. Machine learning tools were employed to assist in the identification and segmentation of images as part of ultrasound data analysis. Statistical analysis revealed significant differences in mean pixel intensity values between fresh and decellularized leaves (

Identifiers

PMID40918368
PMCPMC12409521

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.