ArticleFrontiers in pharmacology2025
Effect of ketamine on cellular immunity and inflammation in patients who undergo laparoscopic colon cancer surgery: a retrospective study.
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Objective: Anesthesia during the surgery impairs immune systems. Ketamine is an anesthetic with immune protective effects. This study intended to investigate the effect of a ketamine-involved anesthetic regimen on cellular immunity and inflammatory cytokines in patients who undergo laparoscopic colon cancer surgery. Methods: This retrospective study screened 60 patients who underwent laparoscopic colon cancer surgery with an anesthesia regimen involving ketamine (N = 30, ketamine group) or not (N = 30, opioid group). Data on surgery-related parameters, blood pressure, heart rate (HR), blood routine examination parameters, cluster of differentiation (CD) 3 Results: The 1 h-postoperative pain score ( Conclusion: A ketamine-involved anesthetic regimen seems to be correlated with the improvement of cellular immunity and inflammation with a tolerable safety profile. However, more studies with a prospective, randomized, controlled design are needed to verify this finding and draw a solid conclusion.
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