Evidence map›Paper›PMID 40918643›Full record

ArticleNAR cancer2025

Analysis of the mRNA modification machinery alterations in breast cancer through the SCAN-B cohort.

Carlos Peula, Margalida Esteva-Socias, Kanchan Kumari, Erik Dassi, Francesca Aguilo

Abstract read
In one paragraph

Article in NAR cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlos PeulaDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123 Trento, Italy.
Margalida Esteva-SociasDepartment of Molecular Biology, Umeå University, 901 87 Umeå, Sweden.
Kanchan KumariDepartment of Molecular Biology, Umeå University, 901 87 Umeå, Sweden.
Erik DassiDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123 Trento, Italy.ORCID 0000-0003-4487-0449
Francesca AguiloDepartment of Molecular Biology, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0002-2374-2045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epitranscriptomic modifications regulate gene expression and have been implicated in cancer, including breast cancer. Using the SCAN-B cohort, we analyzed 49 messenger RNA modification regulators (mRMPs) across breast cancer subtypes. In the basal subtype, we found significant overexpression of m

Indexed as

Breast NeoplasmsRNA, MessengerRNA Processing, Post-TranscriptionalBiomarkers, TumorCohort StudiesFemaleGene Expression Regulation, NeoplasticHumansMethyltransferasesRNA-Binding ProteinsBiomarkers, TumorMethyltransferasesMETTL14 protein, humanRNA-Binding ProteinsRNA, Messenger

Identifiers

PMID40918643
PMCPMC12409412

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.