ArticleCureus2025
Evaluation of Sperm Count Improvement Following Microsurgical Varicocelectomy.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Comparison of Laparoscopic Varicocelectomy and Microsurgical Varicocelectomy with Internal Spermatic Vein-Superficial Epigastric Vein Bypass in Adolescent Patients.Children (Basel, Switzerland) · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVaricocele is a common, correctable cause of male infertility, often associated with impaired spermatogenesis. Microsurgical subinguinal varicocelectomy is considered the gold standard for varicocele repair, with documented benefits on semen quality, particularly sperm count.
objectiveThe objective of this study was to evaluate the effect of microsurgical varicocelectomy on sperm count in infertile men diagnosed with clinical varicocele. METHODOLOGY: This prospective observational study was conducted at the Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar, Pakistan, over six months (October 1, 2024, to March 31, 2025). A total of 100 male patients aged between 20 to 45 years with clinical Grade I-III varicocele and abnormal semen parameters were enrolled. Patients underwent microsurgical subinguinal varicocelectomy after baseline semen analysis. A follow-up semen analysis was performed three months postoperatively. Pre- and postoperative sperm counts were compared using paired t-tests. Subgroup analysis was performed based on varicocele grade and laterality.
resultsThe mean preoperative sperm count was 12.5 ± 6.8 million/mL, which significantly increased to 20.2 ± 8.1 million/mL postoperatively (p < 0.001). Patients with Grade III varicocele showed the highest improvement (22.6 ± 9.1 million/mL, p = 0.003). No significant difference was observed based on laterality (p = 0.087).
conclusionMicrosurgical varicocelectomy significantly improves sperm count in men with clinical varicocele, particularly in higher-grade cases. It should be considered an effective first-line intervention in the management of varicocele-associated male infertility.
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