ArticleFrontiers in veterinary science2025
Feline herpesvirus type 1 infection alters the diversity of upper respiratory tract microbiota in cats.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Feline herpesvirus type 1 (FHV-1) is a primary pathogen causing feline upper respiratory tract diseases (FURTD), but its impact on the upper respiratory tract microbiota remains unclear. This study aimed to evaluate the impact of FHV-1 infection on the upper respiratory tract microbiota by comparing the microbial composition between FHV-1-positive group with FHV-1-negative group. Methods: The microbial diversity in the upper respiratory tract of FHV-1-positive cats ( Results: Sequencing results showed that FHV-1 infection significantly increased microbial diversity (Shannon index: 5.55 ± 0.17 vs. 5.30 ± 0.11, Discussion: This study provided the first evidence that FHV-1 infection significantly alters the diversity and composition of the upper respiratory tract microbiota in cats. These microbiota changes were likely to play an important role in the pathogenesis of FURTD and offer new targets for the development of microbiota-based therapeutic strategies.
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