Evidence map›Paper›PMID 40919257›Full record

ReviewReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2025

Involvement of lncRNA in cancer diagnosis and prognosis and clinical implications.

Chainsee Saini, Prerna Vats, Simran Maharshi, Bhavika Baweja, Rajeev Nema

Abstract readReview
In one paragraph

Review in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Stem cells therapy molecular tracking - the special focus on nuclear medicine.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chainsee SainiDepartment of Biosciences, Manipal University Jaipur, Dehmi Kalan, Jaipur, Rajasthan, India.
Prerna VatsDepartment of Biosciences, Manipal University Jaipur, Dehmi Kalan, Jaipur, Rajasthan, India.
Simran MaharshiDepartment of Biosciences, Manipal University Jaipur, Dehmi Kalan, Jaipur, Rajasthan, India.
Bhavika BawejaDepartment of Biosciences, Manipal University Jaipur, Dehmi Kalan, Jaipur, Rajasthan, India.
Rajeev NemaDepartment of Biosciences, Manipal University Jaipur, Dehmi Kalan, Jaipur, Rajasthan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding ribonucleic acids (lncRNAs) form a subclass of non-coding RNAs (ncRNAs), they are quite long and as their name non-coding suggests they do not have a role in protein coding. lncRNAs are vital in all the key steps of tumorigenesis, such as epithelial-mesenchymal transition, cancer stem cells formation, invasion, migration, and formation of the tumor vasculature. lncRNAs are classified into oncogenic or anti-tumor lncRNAs based on their functions. Moreover, cancer stem cells show an extremely specific pattern of expression of lncRNAs, which can be used for early detection of cancer. Similarly, their pre-treatment expression levels correlate with prognosis as they participate in key tumor biology processes like metastasis and recurrence. This chapter seeks to explore both the association between lncRNA genes and cancer and the role of lncRNAs in cancer initiation and progression. Future questions would focus on what the accepted normal ranges of lncRNA expression will be, where they are present in body fluids, which could help with non-invasive tests. But for now, one thing is clear that lncRNAs could pave the way for novel cancer therapies.

Indexed as

diagnosislncRNAncRNAprognosistherapeutics

Identifiers

PMID40919257
PMCPMC12413237

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.