Evidence map›Paper›PMID 40919813›Full record

ArticlemBio2025

FABP4-dependent fatty acid oxidation-fueled mitochondrial ROS induces the mobilization of cellular iron and facilitates

Kazunari Ishii, Yusuke Kurihara, Michinobu Yoshimura, Nirwana Fitriani Walenna, Akinori Shimizu, Ryo Ozuru, Kenji Hiromatsu

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trypanocidal Activity of Crude Extracts fromJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kazunari IshiiDepartment of Microbiology & Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.ORCID 0000-0001-8696-4959
Yusuke KuriharaDepartment of Microbiology & Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Michinobu YoshimuraDepartment of Microbiology & Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.ORCID 0000-0002-5571-2182
Nirwana Fitriani WalennaDepartment of Microbiology & Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Akinori ShimizuDepartment of Microbiology & Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Ryo OzuruDepartment of Microbiology & Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.ORCID 0000-0002-0616-0190
Kenji HiromatsuDepartment of Microbiology & Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.ORCID 0000-0002-3496-6087

Funding

Japan Society for the Promotion of Science 22K08614Japan Society for the Promotion of Science 23K07932Japan Society for the Promotion of Science 24K10225Japan Society for the Promotion of Science 24K11646
6 · The paper itself

Abstract

Fatty acid-binding protein 4 (FABP4) is a cytosolic lipid chaperone predominantly expressed in adipocytes. It has been shown that

Indexed as

AdipocytesFatty Acid-Binding ProteinsFatty AcidsIronMitochondriaReactive Oxygen SpeciesTrypanosoma cruzi3T3-L1 CellsAnimalsCarnitine O-PalmitoyltransferaseChagas DiseaseMiceOxidation-ReductionCarnitine O-PalmitoyltransferaseFabp4 protein, mouseFatty Acid-Binding ProteinsFatty AcidsIronReactive Oxygen SpeciesadipocyteFABP4fatty acid oxidationlabile iron poolmitochondriaROSTrypanosoma cruzi

Identifiers

PMID40919813
PMCPMC12505895

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.