Evidence mapPaperPMID 40920743Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2025

Cystathionine γ lyase deletion enhances corpus cavernosum contraction via thromboxane A

Tooyib A Azeez, Clifford J Pierre, Colin M Ihrig, Stephen P Chelko, Judy M Muller-Delp, Justin D La Favor

Abstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Tooyib A AzeezDepartment of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0002-8101-2112
Clifford J PierreDepartment of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0002-9992-657X
Colin M IhrigDepartment of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, Florida, United States.
Stephen P ChelkoDepartment of Biomedical Sciences, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0003-1675-5945
Judy M Muller-DelpDepartment of Biomedical Sciences, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0001-5322-0611
Justin D La FavorDepartment of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0002-0845-3421

Funding

Role of Testosterone Induction of Hydrogen Sulfide in Erectile DysfunctionR03DK131242 · NIDDK · FLORIDA STATE UNIVERSITY · PI Justin David LaFavor · 2023 to 2023
$109k
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) K01DK115540HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R03DK131242NIDDK NIH HHS K01 DK115540NIDDK NIH HHS R03 DK131242
6 · The paper itself

Abstract

Cystathionine γ-lyase (CSE) produces hydrogen sulfide (H

Indexed as

Cystathionine gamma-LyaseEndothelium, VascularPenile ErectionPenisThromboxane A2VasoconstrictionAnimalsHydrogen SulfideMaleMiceMice, Inbred C57BLMice, KnockoutMuscle ContractionVasodilationCystathionine gamma-LyaseHydrogen SulfideThromboxane A2erectile dysfunctionhydrogen sulfidemyographpudendal arteryvascular function

Identifiers

PMID40920743
PMCPMC12478327

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.