Evidence map›Paper›PMID 40920766›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2025

Mesenchymal stromal cell extracellular vesicles reduce

Sharanya Sarkar, Roxanna Barnaby, Amanda B Nymon, Lily A Charpentier, Lily Taub, Matthew J Wargo, Daniel J Weiss, Tracey L Bonfield, Bruce A Stanton

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Mesenchymal stromal cells forFrontiers in microbiology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sharanya SarkarDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.ORCID 0000-0002-2459-8620
Roxanna BarnabyDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.
Amanda B NymonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.
Lily A CharpentierDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.ORCID 0000-0002-8440-1850
Lily TaubDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.ORCID 0009-0008-6625-6216
Matthew J WargoDepartment of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, United States.ORCID 0000-0001-5659-749X
Daniel J WeissDepartment of Medicine, University of Vermont, Burlington, Vermont, United States.
Tracey L BonfieldNational Center for Regenerative Medicine, Case Western Reserve University, Cleveland, Ohio, United States.
Bruce A StantonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.ORCID 0000-0002-1661-407X

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI KEITH D. PAULSEN · 1985 to 2026
$91.3M
Zhao - Proj 2P20GM130454 · NIGMS · DARTMOUTH COLLEGE · PI MICHAEL L WHITFIELD · 2019 to 2026
$27.2M
Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Martina Gentzsch · 2004 to 2026
$26.5M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 2018 to 2026
$13.9M
Retrieval, Reprocessing, Normalization and Sharing of Gene Expression and Lung Microbiome Data Sets to Facilitate AI/ML Analysis Studies of Bacterial Lung InfectionsR01HL151385 · NHLBI · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2021 to 2024
$2.4M
Reproducible and FAIR Bioinformatics Analysis of Omics DataR25HG011447 · NHGRI · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI HAMPTON, THOMAS H, STANTON, BRUCE A. · 2021 to 2025
$399k
Acquisition of the NextSeq2000 Sequencing platform to Increase Next Generation Sequencing Throughput While Reducing Costs at DartmouthS10OD030242 · OD · DARTMOUTH COLLEGE · PI KOLLING IV, FRED W · 2021 to 2021
$321k
MDIBL STEER: Pathways of Chemical Action in Human DiseaseR25ES016254 · NIEHS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI STANTON, BRUCE A. · 2008 to 2012
$223k
Host-Pathogen Interactions in a Cystic Fibrosis Polymicrobial Infection ModelF31HL172440 · NHLBI · DARTMOUTH COLLEGE · PI Lily Charpentier · 2024 to 2026
$149k
Cystic Fibrosis Foundation (CFF) BOUCHE19R0Cystic Fibrosis Foundation (CFF) STANTO19G0HHS | National Institutes of Health (NIH) DK065988HHS | National Institutes of Health (NIH) F31HL172440HHS | National Institutes of Health (NIH) P30-DK117469 and R01HL151385HHS | NIH | National Cancer Institute (NCI) 5P30CA023108NCI NIH HHS P30 CA023108NHGRI NIH HHS R25 HG011447NHLBI NIH HHS F31 HL172440NHLBI NIH HHS R01 HL151385NIDDK NIH HHS P30 DK065988NIDDK NIH HHS P30 DK117469NIEHS NIH HHS R25 ES016254NIGMS NIH HHS P20 GM130454NIH HHS S10 OD030242
6 · The paper itself

Abstract

Cystic fibrosis (CF) is a multiorgan disease caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (

Indexed as

Anti-Inflammatory AgentsBiofilmsExtracellular VesiclesMesenchymal Stem CellsMicroRNAsPseudomonas aeruginosaPseudomonas InfectionsCystic FibrosisEpithelial CellsHumansInflammationAnti-Inflammatory AgentsMicroRNAsmirnlet7 microRNA, humancystic fibrosishuman bronchial epithelial cellsinflammationmesenchymal stromal cell extracellular vesiclesPseudomonas aeruginosa biofilms

Identifiers

PMID40920766
PMCPMC12670270

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.