ReviewMetabolic brain disease2025
The therapeutic effects of various tonic traditional Chinese medicines on demyelinating diseases.
Review in Metabolic brain disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Neuroprotective effects of traditional Chinese medicine using zebrafish models - a review.Frontiers in pharmacology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Demyelinating diseases, a prevalent group of neurological disorders, lead to impaired nerve conduction and sensorimotor dysfunctions. Despite existing treatments demonstrating some efficacy, their limitations have driven research toward exploring natural remedies. This review summarizes the therapeutic potential of four traditional tonic Chinese herbal medicines-ginsenosides, deer antler polypeptides, resveratrol, and ginkgo leaf extracts-for demyelinating diseases. The selection of these four components is based on their reported neuroprotective and immunomodulatory effects in recent studies. Ginsenosides can modulate immune functions, counteract oxidative stress, and promote remyelination in demyelinating injuries caused by inflammatory conditions. Deer antler polypeptides facilitate remyelination by regulating the expression of myelin-related proteins. Resveratrol exhibits antioxidant and anti-inflammatory properties, alleviating the symptoms of chronic demyelinating diseases induced by metabolic disturbances. Among the components of ginkgo leaf extracts, flavonoids protect neurons and inhibit apoptosis, while terpene lactones modulate the expression of myelin-related genes. This review summarizes the current research on these tonic Chinese herbal medicines and discusses their potential applications in treating demyelinating diseases. This comprehensive review evaluates the research progress on these essential tonic Chinese herbal medicines, revealing their potential applications in demyelinating disease treatments. It may offer a basis for future investigations and potential implications for clinical research.
Indexed as
Identifiers
40924287What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.