Trial reportJAMA network open2025
Digital Psychological Intervention for Inflammatory Rheumatic Diseases: A Pilot Randomized Clinical Trial.
Trial report in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Psychological Aspects of Rheumatic Diseases: Psychorheumatology in Clinical Practice.Rheumatology and therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: Patients with inflammatory rheumatic diseases (IRDs) frequently experience psychological distress; however, access to psychological support remains limited. Objective: To investigate the effectiveness of a digital psychological intervention for individuals with IRDs. Design, Setting, and Participants: Participants aged 18 years or older were recruited across Germany between February 22 and June 4, 2024, if they had been diagnosed with rheumatoid arthritis, psoriatic arthritis, or systemic lupus erythematosus and reported psychological distress and reduced quality of life. Interventions: Participants were randomized to either a self-guided digital psychological intervention or a treatment-as-usual control condition. Main Outcomes and Measures: The primary outcomes were change in psychological distress (German version of the Hospital Anxiety and Depression Scale) and quality of life (Assessment of Quality of Life-8 Dimensions) from baseline to 3 months. Secondary outcomes included changes in self-efficacy, health literacy, perceived stress, functional impairment, depression, and anxiety. Results: A total of 102 participants (mean [SD] age, 47.2 [12.9] years; 92 [90.2%] female) were randomized to an intervention group (n = 52) or a control group (n = 50). The intervention group showed a significantly greater reduction in psychological distress at the 3-month follow-up (least-squares mean [SE] difference, -3.60 [1.07]; 95% CI, -5.73 to -1.47; P < .001; Cohen d = -0.71) and a greater improvement of quality of life (least-squares mean [SE] difference, 0.04 [0.02]; 95% CI, 0.00-0.09; P = .047; Cohen d = 0.49). A significantly greater number of participants in the intervention group experienced a clinically meaningful improvement in psychological distress (29 [59.2%] vs 17 [34.0%]; P = .02) and quality of life (27 [55.1%] vs 16 [32.0%]; P = .03) compared with the control group. Secondary outcomes measures showed a similar pattern of improvement, except for functional impairment. No adverse events related to the intervention were reported. Conclusions and Relevance: This pilot randomized clinical trial supports the effectiveness and safety of a digital psychological intervention in individuals with IRDs. These findings suggest that such digital interventions could be a valuable, scalable approach to addressing mental health needs in rheumatology. Trial Registration: German Clinical Trials Register (DRKS) identifier: DRKS00032862.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.