Evidence map›Paper›PMID 40925397›Full record

ArticleJournal of breath research2025

Evaluation of lung oxidative stress and inflammatory state using exhaled breath condensate analysis in early-life arsenic exposure.

Jim K Mansoor, Eva Borras, Emily M Wong, Liliana P Rodriguez, Amanda Silveira, Catterina Ferreccio, Cristina E Davis, Craig Steinmaus, Edward S Schelegle

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of breath research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jim K MansoorDepartment of Physical Therapy, School of Health Sciences, University of the Pacific, Stockton, CA, United States of America.ORCID 0009-0002-3094-4160
Eva BorrasDepartment of Mechanical and Aerospace Engineering, University of California, Davis, Davis, CA, United States of America.ORCID 0000-0002-4613-5328
Emily M WongDepartment of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States of America.ORCID 0000-0002-6459-7665
Liliana P RodriguezAdvanced Center for Chronic Diseases, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Amanda SilveiraBerkeley Environmental Health Sciences, University of California, Berkeley, CA, United States of America.
Catterina FerreccioAdvanced Center for Chronic Diseases, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID 0000-0001-6331-5534
Cristina E DavisDepartment of Mechanical and Aerospace Engineering, University of California, Davis, Davis, CA, United States of America.ORCID 0000-0002-9878-7758
Craig SteinmausArsenic Health Effects Research Group, School of Public Health, University of California, Berkeley, CA, United States of America.ORCID 0000-0003-2697-843X
Edward S SchelegleDepartment of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States of America.ORCID 0000-0002-4842-3171

Funding

NIEHS NIH HHS R21 ES027107
6 · The paper itself

Abstract

Millions of people worldwide are exposed to environmental arsenic in drinking water, resulting in both malignant and nonmalignant diseases. Interestingly, early life exposure by itself is sufficient to produce higher incidences of these diseases later in life. Based on the delayed onset of disease, we hypothesized that early life arsenic exposure would also induce long-term alterations in the metabolic profile. The objective of this study was to examine metabolomic biomarkers in exhaled breath condensate (EBC) of individuals exposed to arsenic in drinking water early in life, but not later. One hundred and fifty subjects (75 males and 75 females) were initially recruited from Antofagasta, Chile, some of whom were exposed to high water arsenic levels (⩾870

Indexed as

ArsenicEnvironmental ExposureInflammationLungOxidative StressAdultBiomarkersBreath TestsChileDrinking WaterExhalationFemaleHumansMaleMiddle AgedYoung AdultArsenicBiomarkersDrinking Waterarsenicearly life exposureexhaled breathlung functionmetabolomics

Identifiers

PMID40925397
PMCPMC12539092

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.