Trial reportJournal of medical Internet research2025
Supporting Informal Dementia Caregivers Through an iSupport Web-Based Primary Health Care Intervention: Hybrid Effectiveness-Implementation Mixed Methods Study.
Trial report in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of eHealth Interventions in Alleviating Burden on Informal Caregivers of People With Dementia: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Can the Use of Telehealth Guidance Services Reduce Depressive Symptoms Among Family Caregivers of Older Adults with Cognitive Impairment? A Moderated-Mediation Model.Healthcare (Basel, Switzerland) · 2026Article
- Home-Based Digital Healthcare Interventions for Dementia: A Systematic Review of Patient and Family Caregiver Outcomes.Healthcare (Basel, Switzerland) · 2026Review
- Training needs of informal caregivers of persons with dementia in rural southwestern Uganda: A qualitative formative study.Global mental health (Cambridge, England) · 2026Article
- Mediating effect of family functioning on depressive symptoms and family resilience in dementia caregivers.Frontiers in public health · 2026Article
- Development, Implementation, and Outcomes of Web-Based Interventions for Family Caregivers of Individuals with Dementia: A Scoping Review.Risk management and healthcare policy · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInformal caregivers of home-dwelling people with dementia experience significant unmet needs. However, family physician teams as primary health care gatekeepers for aging populations in China remain an underused resource for structured caregiver support.
objectiveThis hybrid effectiveness-implementation study aimed to evaluate a policy-aligned integration of the World Health Organization's iSupport web-based program with China's family physician contract services for informal dementia caregivers while systematically assessing implementation determinants using the Consolidated Framework for Implementation Research (CFIR).
methodsA cluster randomized controlled trial enrolled 120 informal caregivers of people with dementia in Beijing randomly assigned to either the intervention group (n=60) receiving the family physician team-guided iSupport intervention plus usual care or the control group (n=60) receiving usual care plus only iSupport registration. Caregiver burden (primary outcome) and quality of life, social support, and learning behaviors (secondary outcomes) were assessed at baseline and the postintervention time point. Intention-to-treat analysis was applied. The quantitative data were analyzed using linear mixed models and generalized linear mixed models. Implementation barriers and facilitators were explored through CFIR-guided thematic analysis of semistructured interviews with 34 stakeholders.
resultsThe intervention revealed no substantial between-group differences in caregiver burden (β=-3.80, 95% CI -11.25 to 3.65, P=.32), quality of life (β=-1.55, 95% CI -6.59 to 3.49, P=.55), or social support (β=0.85, 95% CI -2.86 to 4.56, P=.65). However, it demonstrated significantly improved learning behaviors in the intervention group (β=2.35, 95% CI 1.03-3.67; P<.001). CFIR analysis identified multilevel barriers: (1) policy-finance misalignment excluding dementia care from essential services, (2) digital adaptation gaps for older users, (3) lack of performance incentives in primary health care, (4) caregivers' technological and time constraints, and (5) conflicts between standardized content and personalized needs.
conclusionsThis iSupport-based primary health care intervention presents a policy-aligned support model for dementia caregivers in China. While core outcomes showed no significant improvement, enhanced learning behaviors suggest potential for caregiver empowerment. Key implementation insights focused on optimizing digital platforms, strengthening policy incentives, and personalizing support. These findings offer a scalable, policy-aligned model for dementia care management by leveraging primary health care networks, particularly in low- and middle-income countries.
trial registrationChinese Clinical Trial Registry ChiCTR2400084788; https://www.chictr.org.cn/showproj.html?proj=223091.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.