Evidence map›Paper›PMID 40925650›Full record

ArticleAging cell2025

SIRT2 and NAD

Marine Barthez, Zehan Song, Yufan Feng, Yifei Wang, Chih-Ling Wang, Danica Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. A Review ofFoods (Basel, Switzerland) · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marine BarthezDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA.ORCID 0000-0001-6910-0403
Zehan SongDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA.
Yufan FengDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA.ORCID 0009-0009-5980-965X
Yifei WangDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA.
Chih-Ling WangDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA.
Danica ChenDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA.

Funding

Inflammation and Aging-associated DiabetesR01AG063389 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHEN, DANICA · 2019 to 2023
$2.0M
Nutrient Sensing, Hematopoietic Stem Cell Metabolism and AgingR01AG063404 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHEN, DANICA · 2018 to 2022
$2.0M
Hematopoietic Stem Cell AgingR01DK117481 · NIDDK · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHEN, DANICA · 2018 to 2021
$1.7M
Neural Stem Cell Aging and NeurodegenerationR01AG082105 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI DANICA CHEN · 2024 to 2026
$1.7M
National Institute of Food and AgricultureNIA NIH HHS R01 AG063389NIA NIH HHS R01 AG063404NIA NIH HHS R01 AG082105NIH HHS R01AG 063389NIH HHS R01AG063404NIH HHS R01AG082105NIH HHS R01DK 117481
6 · The paper itself

Abstract

Aging leads to chronic inflammation that is linked to aging-associated conditions and diseases. Multiple immune pathways become activated during aging, posing a challenge to effectively reduce aging-associated inflammation. SIRT2, an NAD

Indexed as

AgingInflammationNADSirtuin 2AnimalsHumansMiceMice, Inbred C57BLNADSirt2 protein, mouseSirtuin 2

Identifiers

PMID40925650
PMCPMC12419836

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.