Observational studyDiabetic medicine : a journal of the British Diabetic Association2025
Impact of Omnipod 5 automated insulin delivery on continuous glucose monitoring metrics and predictors of improvement in time in range.
Observational study in Diabetic medicine : a journal of the British Diabetic Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and Safety of Tubeless Hybrid Closed-Loop Systems in Type 1 Diabetes: A Meta-Analysis of Randomized Controlled Trials.Diabetes, obesity & metabolism · 2026Pooled it
- Transitioning to Omnipod 5Biomedicines · 2026Article
- Mind-glucose control interplay in type 1 diabetes: management of exam-related stress using the MiniMed™ 780G insulin pump among high school students.Diabetology & metabolic syndrome · 2026Article
- Impact of Omnipod 5 automated insulin delivery on continuous glucose monitoring metrics and predictors of improvement in time in range.Diabetic medicine : a journal of the British Diabetic Association · 2025Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThis study aimed to assess the impact of the Omnipod 5 automated insulin delivery (AID) system on continuous glucose monitoring (CGM) metrics, HbA1c, and weight in a real-world setting. Additionally, independent predictors of glycaemic response were assessed.
methodsObservational analysis of adults with type 1 diabetes using Omnipod 5 (n = 353). Paired data on CGM metrics (n = 268), HbA1c (n = 193), and weight (n = 173) were collected at baseline and compared after median of 191, 120, and 221 days, respectively. Independent predictors of TIR response (≥5%) and HbA1c (≥5 mmol/mol) were assessed.
resultsOmnipod 5 use was associated with improved TIR (+16%, p < 0.001) and a reduction in HbA1c (-3 mmol/mol, p < 0.001). The greatest improvements (-7 mmol/mol, p < 0.001) were observed in individuals with elevated baseline HbA1c (≥58 mmol/mol). Sensor choice (Dexcom G6 vs. Freestyle Libre 2 Plus) influenced time in full auto mode (94% vs. 96%, p < 0.001) but did not affect the likelihood of improved TIR or HbA1c. Logistic regression identified baseline HbA1c (OR 1.24 per mmol/mol, p < 0.001) as the main association with improved HbA1c. Similarly, baseline TIR was associated with improvement in TIR (OR 0.83 per %, p < 0.001). Greater time in automation and using the lowest glucose target were also associated with improved outcomes.
conclusionsOmnipod 5 is associated with significant and sustained improvements in CGM metrics and HbA1c, particularly in individuals with higher baseline HbA1c. The results suggest the potential benefits of prioritizing AID for individuals at greatest risk of complications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.