ArticleRenal failure2025
Latent class analysis of depression among maintenance hemodialysis patients in China: a multicenter cross-sectional study.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
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9 authors.
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Abstract
backgroundDepression is a common mental disorder in hemodialysis patients. The present study aimed to identify subgroups of patients receiving hemodialysis based on depression and explore the influencing factors in a multicenter hemodialysis population in China.
methodsA total of 1,090 hemodialysis patients (682 men, mean aged 61.5 ± 12.6 years) from 7 facilities in Shanghai of China during 2020-2023. Depression was assessed by Patient Health Questionnaire 9 (PHQ-9). Latent class analysis (LCA) was performed to identify homogeneous groups of depressive symptoms. Analysis of variance and chi-square test were performed to establish class-dependent differences in depression severity. Multinomial logistic regression revealed the associations and related factors on most probable class.
resultsThree latent classes were identified: High depressive symptoms (Class 1,
conclusionsThe current study provides evidence for the heterogeneity of depression severity. A better understanding of depression risk factor profiles could help develop targeted prevention and intervention programs for the hemodialysis population.
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