Evidence map›Paper›PMID 40926224›Full record

ArticleRenal failure2025

U-shaped association of body roundness index with all-cause and cardiovascular mortality in individuals with chronic kidney disease.

Bo Huang, Xinxin Zhang, Hongbao Guo, Cheng Meng, Jingqiu Cui, Junya Jia

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bo HuangDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Xinxin ZhangDepartment of Nephrology, Kidney Disease Medical Center, Tianjin Medical University General Hospital, National Key Clinical Specialty, Tianjin Key Medical Discipline, Tianjin, China.
Hongbao GuoDepartment of Nephrology, Kidney Disease Medical Center, Tianjin Medical University General Hospital, National Key Clinical Specialty, Tianjin Key Medical Discipline, Tianjin, China.
Cheng MengDepartment of Nephrology, Kidney Disease Medical Center, Tianjin Medical University General Hospital, National Key Clinical Specialty, Tianjin Key Medical Discipline, Tianjin, China.
Jingqiu CuiDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Junya JiaDepartment of Nephrology, Kidney Disease Medical Center, Tianjin Medical University General Hospital, National Key Clinical Specialty, Tianjin Key Medical Discipline, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate the association between body roundness index (BRI) and deaths from all causes and cardiovascular disease (CVD) in participants with chronic kidney disease (CKD). MATERIALS AND

methodsThe data was sourced from the National Health and Nutrition Examination Survey (NHANES) 1999-2018. Cox proportional hazards regression along with restricted cubic splines were applied to assess the associations of BRI with deaths from all causes and CVD in individuals with CKD.

resultsIn total, 8,000 individuals were included in the final analysis. In participants with CKD, there was a nonlinear U-shaped association between BRI and deaths from all causes and CVD, with inflection points at 6.29 and 6.04. When BRI was below the inflection points, each unit increment of BRI correlated with a 11% reduction in deaths from all causes [HR: 0.89 (0.84-0.94),

conclusionIn this nationally representative study, we found a nonlinear U-shaped association between BRI and deaths from all causes and CVD among participants with CKD, with inflection points at 6.29 and 6.04. Further research is required to establish the optimal range of BRI as a measure of visceral fat deposition.

Indexed as

Cardiovascular DiseasesRenal Insufficiency, ChronicAdultAgedBody Mass IndexCause of DeathFemaleHumansMaleMiddle AgedNutrition SurveysProportional Hazards ModelsUnited StatesBody roundness indexcardiovascularchronic kidney diseasemortality

Identifiers

PMID40926224
PMCPMC12422039

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.