Evidence map›Paper›PMID 40926839›Full record

ArticleVeterinary world2025

Eco-friendly microencapsulation of

Watcharapong Mitsuwan, Chonticha Romyasamit, Rungruedee Kimseng, Tanakamol Mahawan, Sasi Vimon

Abstract read
In one paragraph

Article in Veterinary world, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Watcharapong MitsuwanAkkhraratchakumari Veterinary College, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Chonticha RomyasamitCenter of Excellence in Innovation of Essential Oil and Bio-active Compound, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Rungruedee KimsengSanders-Brown Center on Aging, College of Medicine, University of Kentucky, Lexington, KY 40506, USA.
Tanakamol MahawanAkkhraratchakumari Veterinary College, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Sasi VimonAkkhraratchakumari Veterinary College, Walailak University, Nakhon Si Thammarat, 80160, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Probiotic viability remains a critical challenge during gastrointestinal (GI) transit, storage, and feed processing. Conventional encapsulation materials often fail under acidic and thermal stress. This study aimed to develop and characterize a novel, eco-friendly microencapsulation system using Materials and Methods: Microcapsules containing LP and FP were formulated through ionic gelation using calcium chloride. Physicochemical properties were assessed using scanning electron microscopy and Fourier-transform infrared (FTIR). Functional evaluations included encapsulation efficiency (EE), swelling kinetics, controlled release in simulated gastric and intestinal fluids, stress tolerance (acid, bile, enzymes, thermal), and viability during 60-day storage at 4°C and 25°C. Results: The LP/FP microcapsules demonstrated high EE (80.5%) and spherical morphology (~200μm). FTIR confirmed the presence of ionic and hydrogen bonding in the matrix. The system exhibited pH-responsive swelling and controlled release, reaching 89.17% cumulative release in intestinal fluid. Encapsulated cells showed significantly improved tolerance to acidic pH, bile salts, digestive enzymes, and heat compared to free cells (p < 0.05). After 60 days, the viability of encapsulated cells remained above 60% at both storage temperatures, while free cell viability dropped by over 85%. Conclusion: FP seed extract offers a biodegradable, plant-derived alternative for probiotic encapsulation. The developed LP/FP system effectively enhances probiotic survival under GI and thermal stress and during extended storage. These results support its application as a sustainable delivery platform for animal feed and functional food formulations.

Indexed as

Ficus pumilagastrointestinal stabilityLacticaseibacillus paracaseiplant-based matrixprobiotic microencapsulationstorage viabilitythermal resistance

Identifiers

PMID40926839
PMCPMC12415121

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.