Evidence map›Paper›PMID 40926887›Full record

ReviewFrontiers in physiology2025

Blood flow restriction training: a new approach for preventing and treating sarcopenia in older adults.

Wei Li, Mingzhen Hu, Qiushi Yin, Yuqing Liu, Lin Chen, Qin Ru, Guodong Xu, Yuxiang Wu

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei Li *Department of Sports Medicine, Wuhan Sports University, Wuhan, China.
Mingzhen Hu *Department of Sports Medicine, Wuhan Sports University, Wuhan, China.
Qiushi YinDepartment of Sports Medicine, Wuhan Sports University, Wuhan, China.
Yuqing LiuDepartment of Sports Medicine, Wuhan Sports University, Wuhan, China.
Lin ChenInstitute of Intelligent Sport and Proactive Health, Department of Health and Physical Education, Jianghan University, Wuhan, China.
Qin RuInstitute of Intelligent Sport and Proactive Health, Department of Health and Physical Education, Jianghan University, Wuhan, China.
Guodong XuInstitute of Intelligent Sport and Proactive Health, Department of Health and Physical Education, Jianghan University, Wuhan, China.
Yuxiang WuDepartment of Sports Medicine, Wuhan Sports University, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the intensification of population aging, sarcopenia in older adults has become a significant public health issue affecting quality of life. Sarcopenia is a progressive and systemic skeletal muscle disorder characterized by reduced muscle mass, decreased muscle strength, and diminished physical function. Although conventional exercise interventions have shown some efficacy in managing sarcopenia, their effects are limited and often insufficient to effectively halt disease progression. Therefore, exploring more efficient exercise interventions is of great importance. Blood flow restriction training (BFRT), as an emerging exercise intervention, has garnered increasing attention in recent years for its application in sarcopenia among older adults. Studies suggest that, compared to traditional resistance exercise, BFRT demonstrates superior effectiveness in improving muscle strength and mass in older adults, potentially serving as a viable alternative to conventional training methods. However, BFRT also presents certain limitations, including potential risks such as cardiovascular responses and muscle injury. Therefore, careful consideration of appropriate application scenarios and exercise loads is crucial during its implementation. This study reviews the biological mechanisms of BFRT in the intervention of sarcopenia and proposes tailored training protocols and application models for older adults. Furthermore, it thoroughly examines the potential risks and applicability of BFRT, aiming to provide theoretical foundations and practical guidance for clinical application. Additionally, the limitations of current research are analyzed, offering recommendations for future research directions.

Indexed as

agingblood flow restriction trainingmuscle massmuscle strengthsarcopenia

Identifiers

PMID40926887
PMCPMC12414948

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.